Aneurysmal Bone Cysts in Young Children

Percutaneous Doxycycline Treatment of Aneurysmal Bone Cysts With Low Recurrence Rate: A Preliminary Report

“…The 5% recurrence rate demonstrated in this series, particularly with juxtaphyseal lesions, provides an acceptable comparative recurrence rate [1,11,16,17,25,28,33,35,36,42,44] with which to pursue further study of this percutaneous treatment option. Furthermore, when recurrence (evidence of residual foci of tumor cells) occurs, patients are able to pursue a minimally invasive option of percutaneous treatment of small recurrent foci.…”

“…In addition, evidence of new bone healing provides key information for the physicians involved that treatment was progressing in the proper direction. Evidence of healing in 100% of patients compares favorably with surgical and nonsurgical care series [1,11,16,17,25,28,33,35,36,42,44].…”

“…The recurrence rate of ABCs after traditional surgical treatments ranges from 12% to 71% (71% in children \ 10 years) with 90% detected within 2 years of surgical treatment [11,16,17,25,28,35,42,44]. Recurrence is particularly associated with juxtaphyseal locations of ABCs in skeletally immature patients [16].…”

Aneurysmal Bone Cysts Recur at Juxtaphyseal Locations in Skeletally Immature Patients

“…Biesecker et al [1] reported a higher rate of recurrence in patients 15 years and younger, whereas other studies report patients younger than 10 years have an increased risk of recurrence [9,10]. In another study, the risk of recurrence was correlated with decreasing age group, and the highest rate of recurrence (75%) was found in children 5 years or younger [17].…”

Case Report: Primary Aneurysmal Bone Cyst of the Epiphysis

“…In a review of seven children with an average age of 5.5 years (range, 2.9-10.6 years), recurrence occurred in five of the seven patients. The recurrences appeared rather rapidly after surgical treatment (average, 8 months) [9]. Proximity of the bone cyst to the physis also might be a risk factor for recurrence owing to the difficulty in complete cyst removal in this area [8].…”