“…2 Despite this, patients often require admission to the intensive care unit (ICU) due to a high rate of complications, including early rebleeding, vasospasm, delayed cerebral ischemia, acute kidney injury (AKI) and hydrocephalus. 2,3 These have been associated with poor outcomes with a fatality rate as high as 51%, especially when considering factors such as level of consciousness on admission, age, and amount of blood on initial imaging 1-3. Although limited investigations have been conducted on the specific impact of AKI on non-traumatic SAH outcomes, AKI is associated with respiratory failure, pneumonia, and increased length of stay (LOS), disability, and mortality 2,4-9. The use of contrast in neuroendovascular imaging and intervention is a known cause of renal impairment in aSAH patients, however the specific etiology of AKI in aSAH patients has yet to be elucidated. 10,11 The Risk, Injury, Failure, Loss, and End-stage renal disease (RIFLE) criteria is utilized frequently in the literature to identify AKI, and was developed by the Acute Dialysis Quality Initiative (ADQI) Group in 2004 to establish consistent and sensitive guidelines for the detection and management of this condition.…”