2013
DOI: 10.1016/j.nano.2013.05.008
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Angelica sinensis polysaccharide nanoparticles as novel non-viral carriers for gene delivery to mesenchymal stem cells

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Cited by 47 publications
(30 citation statements)
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“…NPs based on some green agents like polysaccharides could be a safe and efficient nonviral gene vector to human cells. 58,59 The use of proteins from microorganisms as the reactants and capping agents of noble metals could have some advantages or benefits over other green agents like polysaccharides. First, the noble metal strongly binds to specific amino acids, amine and other metal groups and these complexes are often stronger than with polysaccharide groups.…”
Section: Synthesis Of Aunps and Agnps By Selective Proteinsmentioning
confidence: 99%
“…NPs based on some green agents like polysaccharides could be a safe and efficient nonviral gene vector to human cells. 58,59 The use of proteins from microorganisms as the reactants and capping agents of noble metals could have some advantages or benefits over other green agents like polysaccharides. First, the noble metal strongly binds to specific amino acids, amine and other metal groups and these complexes are often stronger than with polysaccharide groups.…”
Section: Synthesis Of Aunps and Agnps By Selective Proteinsmentioning
confidence: 99%
“…20 In this study, liposome morphology was observed through an H-7650 transmission electron microscope ( Figure 1A and B). The RGPL presented as spherical particles of uniform size dispersed in the solute.…”
Section: Physical Properties Of Rgplmentioning
confidence: 94%
“…This discrepancy is most likely due to the fact that traditional QDs are produced from heavy-metal elements such as PbSe, CdS and CdSe, which suffers from poor biocompatibility and high toxicity [10][11][12][13]. On the other hand, most of the current non-viral gene vectors (such as calcium phosphate nanoparticles [14] and cationic polymers [15,16]) do not possess the property of self-imaging. Therefore, the fabrication of a new type of benign and visible emitter that allows co-operative drug/gene delivery and bioimaging [17] could be an interesting challenge.…”
Section: Introductionmentioning
confidence: 99%