Angio-oedema in a child due to eating tomatoes after exercise

Caffarelli, Carlo; Zinelli, C.; Trimarco, G.; Petroccione, T.; Bernasconi, Sergio

doi:10.1111/j.1365-2230.2005.02013.x

Cited by 6 publications

(3 citation statements)

References 5 publications

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“…Although tomatoes are widely consumed, severe allergic reactions are unusual, or rarely reported. Described allergic manifestations include urticaria/angioedema, dermatitis, oral allergy syndrome (OAS), rhinitis, exerciseinduced anaphylaxis and abdominal pain [8,[20][21][22], whereas non-allergic food hypersensitivity, or food intolerance to tomato has also been reported [23], as well as asymptomatic sensitization. While there is great interest in the study of clinical allergy, the role and exact meaning of sensitization (IgE positivity to an allergen independently of its clinical significance) [24] has been less studied, although there is a rising interest in this area [25].…”

Section: Introductionmentioning

confidence: 99%

Sensitization to tomato peel and pulp extracts in the Mediterranean Coast of Spain: prevalence and co‐sensitization with aeroallergens

Larramendi

Ferrer

Huertas³

et al. 2007

Clin Experimental Allergy

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The prevalence found of skin test sensitivity to tomato is high. Peel extracts detected most of the sensitized subjects. Most of the sensitized subjects were asymptomatic and some patients reported symptoms without skin test sensitivity. Positive subjects were very frequently sensitized to pollens, suggesting allergen cross-reactivity. Regional differences may exist, possibly related to the pattern of sensitization to cross-reacting pollens.

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Section: Introductionmentioning

confidence: 99%

Sensitization to tomato peel and pulp extracts in the Mediterranean Coast of Spain: prevalence and co‐sensitization with aeroallergens

Larramendi

Ferrer

Huertas³

et al. 2007

Clin Experimental Allergy

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“…These include shellfish,9 17 vegetables (celery, tomato),1 18 fruits (apple),19 nuts (pistachio),20 eggs,21 22 seeds and grains including buckwheat. Buckwheat ( Fagopyrum esculentum ) is a pseudo-cereal and is taxonomically unrelated to wheat 23–25.…”

Section: Discussionmentioning

confidence: 99%

Wheat-dependent exercise-induced anaphylaxis: a retrospective case review from a tertiary hospital

Thalayasingam

Allameen

Soh

et al. 2014

Postgraduate Medical Journal

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With the emergence of wheat allergy in East Asian countries, WDEIA has become an important condition for physicians and Singapore is no exception. Under-recognition combined with life-threatening symptoms warrants better public awareness measures. In addition, further studies are necessary to identify possible unique genetic and environmental exposures that could explain the inter-regional differences of WDEIA.

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“…In 30% [1] - 50% of cases [3], EIA occurs only when the subject ingests a particular food before exercise, known as specific food dependent exercise-induced anaphylaxis (FDEIA) [5] or a meal (non-specific FDEIA) prior to exercise [6]. Angioedema and oral allergy syndrome have been reported in an 8 years-old boy who ingested tomatoes after physical exercise [7]. Exercise or food alone do not elicit symptoms.…”

Section: Introductionmentioning

confidence: 99%

Exercise-induced anaphylaxis: A clinical view

Dascola

Caffarelli

2012

Ital J Pediatr

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Exercise-induced anaphylaxis (EIA) is a distinct form of physical allergy. The development of anaphylaxis during exertion often requires the concomitant exposure to triggering factors such as intake of foods (food dependent exercise-induced anaphylaxis) or drugs prior to exercise, extreme environmental conditions. EIA is a rare, but serious disorder, which is often undetected or inadequately treated. This article summarizes current evidences on pathophysiology, diagnosis and management. We reviewed recent advances in factors triggering the release of mediators from mast cells which seems to play a pathogenetic role. A correct diagnosis is essential to avoid unnecessary restricted diet, to allow physical activity in subjects with EIA dependent from triggering factors such as food, and to manage attacks. An algorithm for diagnosing EIA based on medical history, IgE tests and exercise challenge test has been provided. In the long-term management of EIA, there is a need for educating patients and care-givers to avoid exposure to precipitating factors and to recognize and treat episodes. Future researches on existing questions are discussed.

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Angio-oedema in a child due to eating tomatoes after exercise

Cited by 6 publications

References 5 publications

Sensitization to tomato peel and pulp extracts in the Mediterranean Coast of Spain: prevalence and co‐sensitization with aeroallergens

Sensitization to tomato peel and pulp extracts in the Mediterranean Coast of Spain: prevalence and co‐sensitization with aeroallergens

Wheat-dependent exercise-induced anaphylaxis: a retrospective case review from a tertiary hospital

Exercise-induced anaphylaxis: A clinical view

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