Angioceratoma da vulva

Abstract

Angiokeratomas are benign tumors characterized by ectasia of blood vessels in the papillary dermis associated with acanthosis and hyperkeratosis of the epidermis. Dermatological examination of angiokeratomas of Fordyce is characterized by papular keratotic lesions of erythematous-violet color. They are more common in the scrotum, and vulvar involvement is rarely reported. Histopathology is particularly important to distinguish them from other benign and malignant tumors. The article reports the case of a middle-aged black woman with a history of chronic constipation, varicose veins of the lower limbs and cesarean section performed 20 years ago who had had multiple vulvar angiokeratomas for three months. Keywords: Blood vessels; Hemangioma; Skin neoplasms Resumo: Os angioceratomas são tumores benignos caracterizados por ectasia dos vasos sanguíneos da derme papilar associada à acantose e hiperceratose da epiderme. Ao exame dermatológico, os angioceratomas de Fordyce caracterizam-se por lesões papulo-ceratóticas de coloração eritemato-violácea. São mais comuns no escroto, sendo raramente relatada a localização vulvar. A histopatologia é particularmente importante para diferenciá-los de outros tumores benignos e malignos. O artigo relata o caso de uma mulher negra de meia idade com história de obstipação intestinal, varizes de membros inferiores e cesárea há 20 anos que apresentava múlti-plos angioceratomas vulvares há três meses.

Angiokeratoma of Vulva Mimicking Genital Warts

“…Among the localized forms, angiokeratomas of scrotum are the most common. Analogous to angiokeratoma of scrotum, vulvar lesions present as erythematous papules affecting women between 20 and 40 years [2]. Various factors implicated in the pathogenesis of angiokeratoma of vulva include use of contraceptive pills, localized venous hypertension due to varicocele, obesity, and phlebectasia associated with chronic inflammation, radiotherapy, and hysterectomy [1,2].…”

“…Analogous to angiokeratoma of scrotum, vulvar lesions present as erythematous papules affecting women between 20 and 40 years [2]. Various factors implicated in the pathogenesis of angiokeratoma of vulva include use of contraceptive pills, localized venous hypertension due to varicocele, obesity, and phlebectasia associated with chronic inflammation, radiotherapy, and hysterectomy [1,2]. Dermatoscopy and confocal microscopy are useful non-invasive techniques which differentiate angiokeratoma from melanoma, pyogenic granuloma, and angiosarcoma with variable success [1,2].…”

“…Various factors implicated in the pathogenesis of angiokeratoma of vulva include use of contraceptive pills, localized venous hypertension due to varicocele, obesity, and phlebectasia associated with chronic inflammation, radiotherapy, and hysterectomy [1,2]. Dermatoscopy and confocal microscopy are useful non-invasive techniques which differentiate angiokeratoma from melanoma, pyogenic granuloma, and angiosarcoma with variable success [1,2]. Biopsy of angiokeratomas is important for confirmation of diagnosis as these lesions clinically resemble genital warts, malignant melanoma, and seborrheic keratosis.…”

“…Angiokeratoma is usually seen over scrotum and can rarely involve vulva [1,2]. Majority of these lesions are asymptomatic but occasionally can be associated with pruritus, bleeding or dyspareunia.…”

“…Majority of these lesions are asymptomatic but occasionally can be associated with pruritus, bleeding or dyspareunia. Asymptomatic angiokeratoma can be managed conservatively, while symptomatic cases can be treated with various destructive modalities [1,2].…”