Angiofibrolipoma of the oral cavity

Abstract

We describe an unusual and rare case of a lipoma variant known as angiofibrolipoma. A literature search revealed only a few cases of angiofibrolipoma which were located in different anatomical sites; no case of angiofibrolipoma in the oral cavity has been previously reported. We present and discuss the histopatholological-immunohistological findings and features. Angiofibrolipoma histologically consists of mature adipocytes, blood vessels, and bundles of collagenous connective tissue with low to moderate cellularity. It is not encapsulated, but is histologically distinct from surrounding tissue. Positive immunohistological staining with CD-34 presented a large number of blood vessels of different sizes located between collagen fibers and adipocytes. The treatment of choice for a patient with angiofibrolipoma is surgical excision, which is expected to be curative.

Angiolipofibroma: Case report and literature re-review

“…Angiolipofibroma, as a neoplasm is seen in different parts of the body [5][6][7][8][9][10][11][12][13][14][15]. In the gastrointestinal tract, it was reported in buccal mucosa [16], oral cavity [17], esophagus [18], distal duodenum [19], ileum [20], cecum [3,20], colon and rectum [21,22,. The etiology is not clear, but it is believed that it is not a true neoplasm but disorganized overgrowth of mature cells and tissues normally present in the colonic submucosa.…”