Angiogenic factors assessment in pre‐eclampsia high‐risk population for the prediction of small‐for‐gestational age neonates: A prospective longitudinal study

Abstract

Small-for-gestational age (SGA) neonates are at increased risk for perinatal mortality and morbidity. Studies have demonstrated signs of brain reorganization, impaired neurodevelopment, and increased risk of metabolic and cardiac diseases during childhood and adult life. It is well known that prenatal identification of these fetuses is poor. To find strategies to increase prediction of SGA neonates is one of our priorities. 1 Pre-eclampsia (PE) and fetal growth restriction, especially in cases of early presentation, are two entities directly related to placental dysfunction. Maternal characteristics and placental