Angiogenic modulation

Gill, D. G.

doi:10.12968/jowc.1998.7.8.411

Cited by 10 publications

(3 citation statements)

References 11 publications

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“…First, HA provides a temporary structure in the early stages of the wound. 9 This structure helps facilitate the diffusion of nutritional supplies and helps rid the wound of waste products from cell metabolism. Second, and most importantly, HA is closely involved in keratinocyte (cell type of the epidermis or outermost layer of the skin) proliferation and migration.…”

Section: Ha and Its Role In Wound Healingmentioning

confidence: 99%

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Hyaluronic acid derivatives and their healing effect on burns, epithelial surgical wounds, and chronic wounds: A systematic review and meta‐analysis of randomized controlled trials

Voigt

Driver

2012

Wound Repair Regeneration

213

157

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Hyaluronic acid (HA) is a polysaccharide common to most species and is found in many sites in the human body, including the skin and soft tissue. A systematic review of the literature and meta-analysis was performed to identify randomized controlled trials, evaluating the use of HA derivatives in healing burns, epithelial surgical, and chronic wounds. Nine studies were identified, which met the search criteria and clinical endpoints of complete healing and percent wound size reduction when using HA vs. either an active or passive comparator. It was found in the vast majority of randomized controlled trials (eight of nine) that HA derivatives significantly improved the healing of wounds vs. traditional therapies or placebo (either via complete healing or a significant reduction in wound size) occurring from burns, venous insufficiency, diabetes, neuropathic insufficiency, and surgical removal of the epithelial layer (for tattoo removal). In the other remaining trial, one formulation of HA was compared with another, with the higher concentration showing improved application characteristics. Further, it was found in a meta-analysis in subsets of patients with diabetic foot ulcers (neuropathic) that HA derivatives healed these types of wounds significantly faster than standard of care. These studies in aggregate show that HA derivatives accelerate the healing process in burns, epithelial surgical wounds, and chronic wounds.

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Section: Ha and Its Role In Wound Healingmentioning

confidence: 99%

“…HA also provides two very important functions in wound healing as part of cell proliferation and migration. First, HA provides a temporary structure in the early stages of the wound . This structure helps facilitate the diffusion of nutritional supplies and helps rid the wound of waste products from cell metabolism.…”

Section: Introductionmentioning

confidence: 99%

Hyaluronic acid derivatives and their healing effect on burns, epithelial surgical wounds, and chronic wounds: A systematic review and meta‐analysis of randomized controlled trials

Voigt

Driver

2012

Wound Repair Regeneration

213

157

View full text Add to dashboard Cite

show abstract

“…Lo que favorece la formación de tejidos blandos con buena elasticidad y una mayor densidad microvascular 68 . Establece una estructura temporal que facilita la difusión de nutrientes y suministros, lo que ayuda a depurar de la herida de residuos de productos del metabolismo celular y la fagocitosis 69 .…”

Section: Fase Proliferativa O De Granulaciónunclassified

Valoración de la efectividad del ácido hialurónico en la cicatrización de zonas donantes

Vicente¹,

Rosana²

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The Functional Anatomy of the Skin and its Appendages

Storch

Rice

2005

Reconstructive Plastic Surgical Nursing

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Angiogenic modulation

Abstract: A discussion outlining the processes and factors involved in the regulation of angiogenesis

Cited by 10 publications

References 11 publications

Hyaluronic acid derivatives and their healing effect on burns, epithelial surgical wounds, and chronic wounds: A systematic review and meta‐analysis of randomized controlled trials

Hyaluronic acid derivatives and their healing effect on burns, epithelial surgical wounds, and chronic wounds: A systematic review and meta‐analysis of randomized controlled trials

Valoración de la efectividad del ácido hialurónico en la cicatrización de zonas donantes

The Functional Anatomy of the Skin and its Appendages

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