Abstract:Adipose-derived mesenchymal stromal cells (ASCs) hold great potential for cellular therapies by having immunomodulatory behavior and tissue regenerative properties. Due to the capability of ASCs to differentiate into endothelial cells (ECs) and other angiogenic cell types, such as pericytes, ASCs are a highly valuable source for stimulating angiogenesis. However, cellular therapies in tissue engineering have faced challenges in poor survival of the cells after transplantation, which is why a protective biomate… Show more
“…As a result, NFC was able to deliver MSCs for MI therapy. 112 Wu et al co-loaded MSCs and cardioblast cells (H9C2 cells) into chitosan-silk fibroin hydrogel. This co-culture strategy reduced the electrophysiological barriers of native MSCs and released heart-friendly cytokines, which slowed down the acute MI process.…”
Section: Cell or Cell Derivative-laden Hydrogels For MI Therapymentioning
Myocardial infarction (MI) is a global cardiovascular disease with high mortality and morbidity. To treat acute MI, various therapeutic approaches have been developed, including cells, extracellular vesicles, and biomimetic nanoparticles....
“…As a result, NFC was able to deliver MSCs for MI therapy. 112 Wu et al co-loaded MSCs and cardioblast cells (H9C2 cells) into chitosan-silk fibroin hydrogel. This co-culture strategy reduced the electrophysiological barriers of native MSCs and released heart-friendly cytokines, which slowed down the acute MI process.…”
Section: Cell or Cell Derivative-laden Hydrogels For MI Therapymentioning
Myocardial infarction (MI) is a global cardiovascular disease with high mortality and morbidity. To treat acute MI, various therapeutic approaches have been developed, including cells, extracellular vesicles, and biomimetic nanoparticles....
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