Angiographic Efficacy of the Atriclip Left Atrial Appendage Exclusion Device Placed by Minimally Invasive Thoracoscopic Approach

Abstract

Angiographic LAA closure efficacy with a TT-placed Atriclip is high (93.9%). The clinical significance of a remnant stump is unknown. Confirmation of complete LAA occlusion should be made before cessation of systemic anticoagulation.

Left atrial appendage clipping as an adjunctive therapy in lung cancer surgery for patients with atrial fibrillation: a case report

“…Epicardial clipping using the AtriClip™ device has consistently been shown to produce high rates of complete LAA closure, with success rates of >95% reported across a number of studies [5, 6, 7]. These studies also report exceptionally low rates of device-related complications, and low rates of post-operative bleeding and peri-operative stroke.…”

Surgical Closure of the Left Atrial Appendage: The Past, The Present, The Future

“…Most importantly, no strokes, TIAs, or other neuro events (aside from a single, unrelated TIA 2 years postoperatively in a patient with a carotid plaque) were reported. Very recently, a totally thoracoscopic approach for AtriClip placement has been reported with a 94% success rate at 3-months as evaluated by CT, proving the feasibility of performing LAA occlusion as a stand-alone procedure in select patients [22] . Further studies of AtriClip and other LAA occlusion devices are on the horizon and will certainly be informative regarding the safety and effectiveness of these devices.…”

Revisiting Antiarrhythmic Drug Therapy for Atrial Fibrillation: Reviewing Lessons Learned and Redefining Therapeutic Paradigms

“…Various refinements beyond pulmonary vein isolation, including complex fractionated atrial electrograms (CFAEs), focal impulse and rotor modulation (FIRM), electrocardiographic imaging (ECGI), have been explored but met with variable, inconsistent success (Weiss et al, 2016). For left atrial appendage occlusion, the AtriClip device has gained increasing popularity over the last decade as a safe and efficacious alternative to surgical closure and can be easily deployed during concomitant open chest surgery or standalone minimally invasive procedure (Ellis et al, 2017;Caliskan et al, 2018;Toale et al, 2019).…”

“…The Two-pore-domain Weak Inward rectifying K + channel (TWIK)-related Acid- S ensitive K + channel-1 (TASK-1; K 2P 3.1) is a member of the K2P channel family ( Enyedi and Czirják, 2010 ). Because TASK-1 channels are abundant in human atria but not in ventricles ( Heijman et al, 2017 ; Schmidt et al, 2017 ), TASK-1 channels regulate atrial action potential duration ( Limberg et al, 2011 ).…”