Angiographic evidence of progressive lumen narrowing over 2years following drug-eluting stent implantation

Park, Seung‐Jung; Kim, Young‐Hak; Kim, Won‐Jang; Ahn, Jung‐Min; Yun, Sung‐Cheol; Lee, Jong‐Young; Park, Duk‐Woo; Kang, Soo–Jin; Lee, Seung-Whan; Lee, Cheol Whan; Park, Seong-Wook

doi:10.1016/j.ijcard.2010.08.032

Cited by 3 publications

(3 citation statements)

References 26 publications

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“…It might suppose that the healing process in SES implanted struts continued to proceed for up to 2 years. Previous angiographic study reported similar results of progressive lumen narrowing over 2 years following SES implantation [19]. Small amount of increased late loss between 6 month and 2 years may have protective effect against very late stent thrombosis.…”

Section: Discussionsupporting

confidence: 60%

Long-term (≥2 years) follow-up optical coherence tomographic study after sirolimus- and paclitaxel-eluting stent implantation: comparison to 9-month follow-up results

Kim

et al. 2010

Int J Cardiovasc Imaging

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Many studies have demonstrated that late or very late thrombosis after drug-eluting stent (DES) implantation may be related with incomplete neointimal coverage. We investigated long-term (≥2 years) results of neointimal coverage following sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) implantation using optical coherence tomography (OCT). A follow-up angiography with OCT examination was performed in 29 patients with 32 lesions for more than 2 years (group 1; 1,066 ± 381 days) and 101 patients with 104 lesions at 9 months (group 2; 273 ± 33 days) after the index procedure. The status of neointimal coverage and stent apposition was evaluated. The number of stents with completely covered struts was higher (25.0% in group 1 vs. 13.5% in group 2, P = 0.12). The percentage of uncovered struts (5.4 ± 7.5% in group 1 vs. 8.5 ± 11.6% in group 2, P = 0.19) and that of malapposed strut (0.5 ± 1.4% vs. 1.5 ± 4.2%, respectively, P = 0.19) were lower in group 1. While the percentage of uncovered and malapposed struts were quite similar in the PES groups between the two groups (P = 0.54 and 0.65, respectively), there were lower trends in the percentage of uncovered and malapposed struts in the SES group (P = 0.09 and 0.09, respectively). In conclusion, incomplete neointimal coverage was still observed in a majority of DESs and considerable struts were not covered with neointima even at more than 2 years after DES implantation. The pattern of neointimal coverage between 9-month and 2-year appeared to be somewhat different between PES and SES.

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Section: Discussionsupporting

confidence: 60%

Long-term (≥2 years) follow-up optical coherence tomographic study after sirolimus- and paclitaxel-eluting stent implantation: comparison to 9-month follow-up results

Kim

et al. 2010

Int J Cardiovasc Imaging

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“…The 2‐year angiographic evaluation of the SPIRIT II and Taxus II trials showed that late lumen loss from the first to second angiographic follow‐up after PES implantation was not additive . Recently, two large registry studies revealed that lumen diameter following SES and PES implantation progressively narrowed over 2 years . These cumulative findings indicate that long‐term luminal changes after DES implantation are not uniform, but diverse.…”

Section: Discussionmentioning

confidence: 99%

Long‐term luminal change after drug‐eluting stent implantation: Serial angiographic follow‐up study of the ZEST randomized trial

Park

Kim

et al. 2012

Cathet Cardio Intervent

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“…The 2-year angiographic evaluation of the SPIRIT II and Taxus II trials showed that late lumen loss from the first to second angiographic follow-up after PES implantation was not additive [16,17]. Recently, two large registry studies revealed that lumen diameter following SES and PES implantation progressively narrowed over 2 years [18,19]. These cumulative findings indicate that long-term luminal changes after DES implantation are not uniform, but diverse.…”

Section: Discussionmentioning

confidence: 99%

AS-070 Long-Term Luminal Change after Drug-Eluting Stent Implantation; Serial Angiographic Follow-up Study of the ZEST Randomized Trial

Park

Kim

et al. 2012

The American Journal of Cardiology

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Angiographic evidence of progressive lumen narrowing over 2years following drug-eluting stent implantation

Cited by 3 publications

References 26 publications

Long-term (≥2 years) follow-up optical coherence tomographic study after sirolimus- and paclitaxel-eluting stent implantation: comparison to 9-month follow-up results

Long-term (≥2 years) follow-up optical coherence tomographic study after sirolimus- and paclitaxel-eluting stent implantation: comparison to 9-month follow-up results

Long‐term luminal change after drug‐eluting stent implantation: Serial angiographic follow‐up study of the ZEST randomized trial

AS-070 Long-Term Luminal Change after Drug-Eluting Stent Implantation; Serial Angiographic Follow-up Study of the ZEST Randomized Trial

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