Angiography and Scintigraphy of Human Pancreatic Allografts

Svahn, Tony; Lewander, R.; Härdstedt, C; Lundgren, G; Sundelin, P.; Cg, Groth

doi:10.1177/028418517801900202

Cited by 10 publications

(2 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Decreased function Could mean rejection is occurring or that the antiexocrine treatment has succeeded. Angiography was reported by Svahn et al [7] to show characteristic changes of rejection similar to those of renal transplants, namely, arterial irregularities and thromboses. None of the patients undergoing angiography in our series had rejection.…”

Section: Discussionmentioning

confidence: 85%

Radiology of the human segmental pancreatic transplant

Crass

Feinberg

Sutherland

et al. 1982

Gastrointest Radiol

View full text Add to dashboard Cite

Twenty-three segmental pancreatic transplants have been performed for treatment of diabetes mellitus between July 1978 and March 1981 at the University of Minnesota. The radiologic evaluation of the transplants included ultrasonography, 1SSe-methionine isotope scanning, angiography, and CT scanning. Transplants of normal appearance by these studies had normal endocrine function. Pathologic findings are presented and their significance discussed.

show abstract

Section: Discussionmentioning

confidence: 85%

Radiology of the human segmental pancreatic transplant

Crass

Feinberg

Sutherland

et al. 1982

Gastrointest Radiol

View full text Add to dashboard Cite

show abstract

“…Recent studies in the dog have confirmed that rejection may afflict first the exocrine, and then the endocrine portion of the graft (31). Aid in the differential diagnosis between rejection and other conditions causing pancreatic graft malfunction can be obtained by angiography: with rejection the graft vasculature shows characteristic destructive changes (39). The final option is open biopsy, a method often applied by the Minnesota group (35).…”

Section: Graft Rejectionmentioning

confidence: 99%

Pancreatic Transplantation

Tydén

Groth

1986

Int J Technol Assess Health Care

View full text Add to dashboard Cite

In the last few years there has been considerable improvement in results with pancreatic transplantation. Several centers now report a 1-year graft survival rate of 50%-60%. Patients with well-functioning grafts become insulin independent and have normal or near normal fasting ans post-prandial glucose levels and normal glycosylated hemoglobin values. The glucose tolerance as measured by oral and intravenous glucose tolerance tests is normal in 50%-80% of the patients but subnormal in the others. One important reason for subnormal glucose tolerance is medication with cyclosporin and prednisolone. In most cases an improvement in neuropathy is found and retinopathy seems to be stabilized. Preliminary data indicate that the provision of a pancreatic graft prevents the occurrence of diabetic nephropathy in a simultaneously or previously transplanted kidney.

show abstract

Sonography of the segmental human pancreatic transplant

Crass

Sutherland

Feinberg

1982

J of Clinical Ultrasound

View full text Add to dashboard Cite

Forty-three ultrasound examinations have been done on 17 segmental pancreatic transplants performed for juvenile onset diabetes mellitus. The pelvic transplant was readily studied by both real-time and articulated-arm techniques. Transplants of normal sonographic appearance had normal endocrine function. "he most common finding was peripancreatic fluid ranging from a slight halo above the transplant to tense pancreatic ascites-the result of the functional exocrine pancreas' normal function. Indexing Words: Diabetes mellitus Sonography has become a major tool in evaluation of the pancreas and its pathologic states.' It was, therefore, not surprising when we found ultrasound the most often utilized radiologic investigation of the segmental pancreatic transplant in our institution.2 By March 1981 over 40 human segmental pancreatic transplants had been performed at the University of Minnesota for severe juvenile onset diabetes m e l l i t~s ,~ approximately 25% of the world experience to date.4 This report concerns the sonographic findings in the 23 transplants that have been done between July 1978 and March 1981. MATERIAL AND METHODSTwenty-three separate human pancreatic allografts have been performed in 20 patients. Clinical data on this group had previously been reported,2 but some points are worthy of repetition here. "he transplants were from both cadaver and living related donors. The transplant consisted of the distal pancreas with the splenic artery and vein, and was placed intraperitoneally . Vascular anastomoses were to the iliac vessels; since the majorFrom the Departments of Radiology,',a and Surgery,z University of Minnesota Hospitals, Minneapolis, Minnesota.

show abstract

Angiography and Scintigraphy of Human Pancreatic Allografts

Cited by 10 publications

References 2 publications

Radiology of the human segmental pancreatic transplant

Radiology of the human segmental pancreatic transplant

Pancreatic Transplantation

Sonography of the segmental human pancreatic transplant

Contact Info

Product

Resources

About