Angiolymphoid hyperplasia with eosinophilia treated with anti-interleukin-5 antibody (mepolizumab)

A Long-Term Follow-Up of Angiolymphoid Hyperplasia with Eosinophilia Treated by Corticosteroids: When a Traditional Therapy is Still Up-to-Date

“…Continuous wave carbon dioxide and argon lasers have been successfully used, but there is a risk of scarring after treatment. Anecdotal reports have described other successful therapeutic options: intralesional interferon alpha-2a [7], indomethacin farnestil, pentoxifylline, chemotherapeutic agents such as vinblastine, mepolizumab (anti-interleukine-5) and imiquimod [8, 9]. Furthermore, oral retinoids have been employed with different results [2].…”

Angiolymphoid hyperplasia with eosinophilia: report of nine cases

“…Many approaches to treat ALHE have been tried. These include conventional therapies such as steroids (local and systemic), methotrexate, pentoxifylline, propranolol, isotretinoin, cryotherapy, thalidomide phototherapy, or surgical excision, as well as new therapies targeting cytokines including topical imiquimod, interleukin‐5 (mepolizumab), vascular endothelial growth factor‐A (bevacizumab), and interferon alpha‐2a . Laser therapy has also been used to treat ALHE lesions such as pulsed dye laser, carbon dioxide laser, and argon laser .…”

Angiolymphoid hyperplasia with oeosinophilia showing promising result with intralesional radio-frequency ablation therapy: A new cost-effective and hassle-free modality of treatment

“…Photodynamic therapy, electrocautery, cryosurgery and intralesional corticosteroids, interferon alfa-2a, lasers have shown some success. [1234] Although there are many modalities available in the treatment of ALHE, showing variable results, none of them are completely satisfactory and cost-effective.…”