Angiomatoid Fibrous Histiocytoma in the Forearm: A Case Report

Abstract

Background: Angiomatoid fibrous histiocytoma [AFH] is a rare soft tissue tumor most commonly occurring in children, adolescents, and young adults. It is considered to be a tumor of intermediate malignancy because of its less aggressive course. The extremities are the most common site of involvement, followed by the trunk and head and neck.

Intracranial temporal bone angiomatoid fibrous histiocytoma: illustrative case

“…5 Thus far, the majority of reported cases of AFH have occurred in the superficial soft tissues, with relatively few reports in bone 6 and even fewer with intracranial presentation. [7][8][9][10][11] The rarity of AFH makes prospective diagnosis challenging, and the lesion has been mistaken for other pathologies, including angiosarcoma, eosinophilic granuloma, 2,12 meningioma, 10 aneurysmal bone cyst, 13 or cavernous malformation. 7 In this report, we present a rare case of primary AFH in the temporal bone, which, to our knowledge, is the first case of the histological diagnosis of AFH in this location.…”