Angiomatosis: A rare vascular proliferation of head and neck region

Abstract

Angiomatosis is a diffuse vascular lesion which clinically mimics hemangioma or vascular malformation. It usually involves multiple tissues and is histopathologically characterised by proliferation of vessels of varying calibre intimately admixed with large amount of adipose tissue. Its surgical removal is very difficult because of its infiltrative nature. Therefore, a precise histopathological diagnosis is of utmost importance. It is usually seen in females in the first two decades and commonly involves lower extremities. Angiomatosis of head and neck region is very rare. Here we present a rare case of angiomatosis of the lower face involving right cheek and lip in a 4-year-old boy clinically diagnosed as hemangioma. Histopathological differential diagnosis of angiomatosis is also discussed.

Cutaneous angiomatosis in a dog: a case report

“…The cells lining the vessels were identified as well-differentiated endothelial cells. These histopathological findings were consistent with previous findings in humans and dogs with cutaneous angiomatosis [2,11].…”

“…The right hindlimb lesions in this dog were elevated with diffuse red to purple discoloration, similar to the gross lesion reported previously in canine cutaneous angiomatosis [2]. Cutaneous angiomatosis in humans usually occurs in the lower extremities, followed by the chest wall, abdomen, and upper extremities [11]. On the other hand, the reported dog also had lesions on the extremities [2].…”

“…The first is the haphazard proliferation of varying-sized vessels and clusters of capillary vessels adjacent to the vein walls. The second is a central large vessel surrounded by clusters of capillary-sized vessels arranged in nodules [11]. In the present case, mild spongiosis was observed in the epithelium, and vascular proliferation with vasodilation of the upper dermis and inflammatory cell infiltration into the peripheral tissues were observed.…”

Chest wall resection for a giant angiomatosis lesion: A case report

“…Angiomatosis can affect any soft tissue in the body and is defined as a benign vascular lesion that usually presents in the first two decades of life. Angiomatosis typically has a female predilection and tends to involve the lower extremities [ 7 ]. It is histologically characterized by a proliferation of blood vessels of varying sizes.…”