Angioødem – udredning og behandling

Rasmussen, Eva Rye; Bindslev‐Jensen, Carsten; Bygum, Anette

doi:10.4045/tidsskr.12.0470

Cited by 18 publications

(11 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…DRESS may mimic angioedema due to its clinical manifestation with facial or more widespread edema, which is accompanied by a diffuse, morbilliform rash (fig. 2) [17]. Other characteristic findings include fever, eosinophilia, lymphadenopathy and internal organ involvement, mainly the liver and kidneys, which differentiate this condition from angioedema.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

How Not to Be Misled by Disorders Mimicking Angioedema: A Review of Pseudoangioedema

Andersen¹,

Longhurst

Rasmussen

et al. 2016

Int Arch Allergy Immunol

Self Cite

View full text Add to dashboard Cite

Background: Angioedema is a vascular reaction involving the lower dermis, subcutis and/or submucosal tissue and causing a temporary localized swelling in any part of the body. For many health care professionals, the diagnosis presents an ongoing challenge; several disorders may manifest with subcutaneous or submucosal swelling and falsely be assumed to be angioedema. The clinicians at the emergency department and in the immunology/allergy clinics must be skilled at recognizing the features of angioedema and its differential diagnosis. Methods: The review is based on a literature search with specific indexing terms in PubMed, a review of bibliographies and the authors' clinical experience. Results: The most essential diseases that mimic angioedema, the so-called pseudoangioedemas, will each be discussed and illustrated by clinical photos, pointing out key features that help clarify the diagnoses and differentiate these from classic angioedema. Conclusions: A variety of dermatologic conditions can cause swelling that resembles angioedema, some with a potentially fatal outcome if misdiagnosed. Knowledge of pseudoangioedema is fundamental in the emergency setting when handling patients with edema and should be kept in mind when assessing an atypical angioedema case.

show abstract

Section: Resultsmentioning

confidence: 99%

“…When generalized nonpitting edema (myxedema) becomes a manifestation, periorbital edema is often seen as a symptom. Nonetheless, it is not transient like angioedema [10,17]. Identification of the diagnosis is based on clinical features and low levels of thyroid hormones.…”

Section: Resultsmentioning

confidence: 99%

How Not to Be Misled by Disorders Mimicking Angioedema: A Review of Pseudoangioedema

Andersen¹,

Longhurst

Rasmussen

et al. 2016

Int Arch Allergy Immunol

Self Cite

View full text Add to dashboard Cite

show abstract

“…[ 1 ] There are different causes of angioedema, such as the intake of drugs, allergies, or the lack of the complement C1 inhibitor. [ 2 ] Drug-induced angioedema has been reported as an adverse effect of many different drugs. Among them, the use of angiotensin-converting enzyme inhibitor (ACEI) was one of the most common causes of severe angioedema presenting at hospitals.…”

Section: Introductionmentioning

confidence: 99%

Sirolimus-induced severe small bowel angioedema

Yang

Wang

et al. 2018

Medicine

View full text Add to dashboard Cite

Rationale:Drug-induced angioedema has been reported as an adverse effect of many different drugs. But small bowel angioedema associated with sirolimus (SRL) used was barely understood. It must be necessary to report a case suffering from small bowel angioedema with detailed discussion and literature review.Patient concerns:A 38-year-old Chinese woman presented with generalized gastric pain in the following day after renal transplantation. The patient began to crampy abdominal pain accompanied by nausea, vomiting, and diarrhea on postoperative day 6 (POD).Diagnoses:We strongly suspected the angioedema was an adverse reaction to SRL.Intervention:The immunosuppressive regimen was switched from tacrolimus (TAC), SRL, and prednisone to TAC, mycophenolate and prednisone.Outcomes:The symptoms were relieved within next 48 hours after withdrawing the SRL. One more CT scan showed complete resolution of bowel wall thickening and ascites.Lessons:This was the first report of small bowel angioedema associated with SRL. Drug-induced-angioedema is a relatively common presentation and is potentially fatal. It must be aware of potential adverse effects.

show abstract

“…More than 40 million people worldwide are currently treated with angiotensin converting enzyme- (ACE-) inhibitors due to cardiovascular or renal disease [ 1 ]. The primary mechanism of angiotensin converting enzyme-inhibitor related angioedema (ACEi-AE) is accumulation of bradykinin ( Figure 1 ).…”

Section: Introductionmentioning

confidence: 99%

“…The primary mechanism of angiotensin converting enzyme-inhibitor related angioedema (ACEi-AE) is accumulation of bradykinin ( Figure 1 ). The incidence is reported to be 0.1–2.2% of exposed individuals [ 1 , 2 ]. Thus, more than 400,000 cases of angioedema are to be expected worldwide yearly.…”

Section: Introductionmentioning

confidence: 99%

The Use of Plasma-Derived Complement C1-Esterase Inhibitor Concentrate (Berinert®) in the Treatment of Angiotensin Converting Enzyme-Inhibitor Related Angioedema

Hermanrud

Duus

Bygum

et al. 2016

Case Reports in Emergency Medicine

Self Cite

View full text Add to dashboard Cite

Angioedema of the upper airways is a severe and potentially life-threatening condition. The incidence has been increasing in the past two decades, primarily due to pharmaceuticals influencing the generation or degradation of the vasoactive molecule bradykinin. Plasma-derived C1-esterase inhibitor concentrate is a well-established treatment option of hereditary and acquired complement C1-esterase inhibitor deficiency, which are also mediated by an increased level of bradykinin resulting in recurrent angioedema. We here present a case of severe angiotensin converting enzyme-inhibitor related angioedema (ACEi-AE) of the hypopharynx that completely resolved rapidly after the infusion of plasma-derived C1-inhibitor concentrate adding to the sparse reports in the existing literature.

show abstract

Angioødem – udredning og behandling

Abstract: Angioedema is a potentially life-threatening condition and should be assessed and treated systematically. It is important to remember that angioedema is either histaminergic or non-histaminergic, as the treatment of the two types is different.

Cited by 18 publications

References 37 publications

How Not to Be Misled by Disorders Mimicking Angioedema: A Review of Pseudoangioedema

How Not to Be Misled by Disorders Mimicking Angioedema: A Review of Pseudoangioedema

Sirolimus-induced severe small bowel angioedema

The Use of Plasma-Derived Complement C1-Esterase Inhibitor Concentrate (Berinert®) in the Treatment of Angiotensin Converting Enzyme-Inhibitor Related Angioedema

Contact Info

Product

Resources

About