Angiosarcoma-like presentation of pacemaker-related vascular proliferation

Abstract

A 90-year-old man presented with a rapidly growing vascular lesion after a pacemaker generator change. The rapid growth suggested a possible angiosarcoma. A less dramatic presentation of vascular proliferation has been described as reticular telangiectatic erythema, which has been reporting following insertion of pacemakers, implantable cardioverter defibrillators, and drug-delivery devices. The onset of the disorder is described as weeks to years after implantation or generator change. It is a benign condition that generally remains static or regresses over time. The vascular proliferation noted in this case resolved almost completely over a period of 1 year.

Skin lesions over the pocket area that may mimic cardiac implantable electronic device infection: A case series

“…In fact, numerous cases of malignant tumors over the pocket area have been described in the literature. These include melanomas, sarcomas, squamous cell carcinomas, breast carcinomas, plasmacytomas, non‐Hodgkin's lymphomas, and fibroxanthomas . Treatment should be tailored to the underlying neoplastic disorder and prognosis depends on the specific malignancy.…”

“…These include melanomas, sarcomas, squamous cell carcinomas, breast carcinomas, plasmacytomas, non-Hodgkin's lymphomas, and fibroxanthomas. [17][18][19][20][21][22][23][24][25][26][27] Treatment should be tailored to the underlying neoplastic disorder and prognosis depends on the specific malignancy. Titanium is the main material used for manufacturing CIED generator case and is considered an inert material with excellent in vivo tolerance and no clinical evidence of carcinogenic action.…”