Angiotensin-Converting Enzyme Inhibitor Usage in Patients with Incidental Atherosclerotic Renal Artery Stenosis

Two Cases of Renovascular Hypertension and Ischemic Renal Dysfunction: Reliable Choice of Examinations and Treatments

“…Similarly, the systemic R-A system is not always activated in the chronic phase of renovascular hypertension associated with renal failure. However, angiotensin-converting enzyme (ACE) inhibitors and angiotensin II (AII) receptor antagonists have beneficial effects in more than 80% of patients with renovascular hypertension (10). Therefore, the intrarenal R-A system may be enhanced in patients with RAS-induced hypertension although the systemic R-A system is not.…”

Predictors of Undiagnosed Renal Artery Stenosis among Japanese Patients with Risk Factors of Atherosclerosis

“…This prevalence was similar to that reported for the Caucasian population, in which the prevalence of ARAS has also been reported to be high in patients with CAD (15). A high prevalence of ARAS in patients with CAD was also reported in a cohort of Asians that included Japanese (5,10,11). Because these studies reported a correlation between CAD severity and concomitant ARAS, ARAS should be detected and adequately treated to reduce the mortality rate in patients with CAD (16).…”

“…Because of its progressive nature in the absence of adequate treatment, early detection of ARAS is mandatory to reduce the rate of dialysis induction (2). However, because antihypertensive agents that block the renin-angiotensin-aldosterone cascade have made blood pressure control possible even in patients with ARAS, patients with ARAS are often asymptomatic and many cases of ARAS are not detected until ESRD (3,5). Therefore, appropriate clinical indicators to detect ARAS at its early stage are required.…”

Renal Artery Stenosis in Cardio-and Cerebrovascular Disease Renal Duplex Ultrasonography as an Initial Screening Examination

“…Consequently, patients with RAS may often be asymptomatic and untreated. According to Rihal et al 16 and Yang et al, 17 46% of Western patients and 75% of Chinese patients with undiagnosed RAS were taking ACE inhibitors. In our study, ACE inhibitor and/or ARB medication was prescribed for 42.9% of Japanese patients with undiagnosed RAS.…”