Angiotensin-converting enzyme inhibitors in congestive heart failure

Essential Hypertension: Evaluation and Treatment

“…ACE inhibitors reduce left ventricular mass, and are cardioprotective and theoretically anti-anginal as well as anti-dysrhythmic (Deedwania, 1990). ACE inhibitors effectively treat hypertension and congestive heart failure, and are especially efficacious for hypertensive diabetics (Tuck, 1990).…”

“…Following myocardial infarction, ACE inhibitors reduce ventricular enlargement and filling pressures (Goldstein, 1989). ACE inhibitors dramatically improve ventricular hemodynamics, exercise tolerance, and quality of life (Deedwania, 1990;Messerli, 1990a).…”

“…Baseline complete blood count with differential should be reviewed prior to starting ACE inhibitor therapy. In high risk patients, leukocyte counts should be performed every 2 weeks (Deedwania, 1990).…”

“…A patient who grasps the potential risks and complications of high blood pressure on target organ function may be the most compliant patient long-term. Oncedaily dosing may optimize drug compliance in patients who otherwise forget second, third, or fourth daily doses (Eisen, Miller, Woodward, Spitznage, & Przybeck, 1990). Effective blood pressure control and target organ preservation require intensive patient education as well as appropriate and individualized drug therapy (Zeller, Kuhnert, 8c Matthews, 1989…”