Ångstrom-scale silver particles ameliorate collagen-induced and K/BxN-transfer arthritis in mice via the suppression of inflammation and osteoclastogenesis

He, Ze-Hui; Zou, Jing-Tao; Chen, Xia; Gong, Jiang-Shan; Chen, Ya; Jin, Ling; Liu, Yi-Wei; Rao, Shan-Shan; Yin, Hao; Tan, Yi-Juan; Wang, Zun; Du, Wei; Li, Hong-Ming; Qian, Yu-Xuan; Wang, Zhen-Xing; Wang, Yi-Yi; Wan, Teng-Fei; Luo, Yi; Zhu, Hao; Chen, Chun-Yuan; Xie, Hui

doi:10.1007/s00011-023-01778-0

Inflamm. Res.

2023

DOI: 10.1007/s00011-023-01778-0

|View full text |Cite

Ångstrom-scale silver particles ameliorate collagen-induced and K/BxN-transfer arthritis in mice via the suppression of inflammation and osteoclastogenesis

Ze-Hui He,

Jing-Tao Zou,

Xia Chen

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2025

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Hyaluronic Acid‐Based Reactive Oxygen Species‐Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing

Shi,

Zhang,

et al. 2023

Adv Healthcare Materials

View full text Add to dashboard Cite

Diabetic wounds are more likely to develop into complex and severe chronic wounds. The objective of this study is to develop and assess a reactive oxygen species (ROS)‐responsive multifunctional injectable hydrogel for the purpose of diabetic wound healing. We successfully synthesized a multifunctional hydrogel (HA@Cur@Ag) with dual antioxidant, antibacterial, and anti‐inflammatory properties by crosslinking thiol hyaluronic acid (SH‐HA) and disulfide‐bonded hyperbranched polyethylene glycol (HB‐PBHE) through Michael addition while incorporating curcumin liposomes and silver nanoparticles (AgNPs). The HA@Cur@Ag hydrogel exhibited favourable biocompatibility, degradability and injectivity. The outcomes of in vitro and in vivo experiments demonstrated that the hydrogel could effectively be loaded with and release curcumin liposomes, as well as silver ions, thereby facilitating diabetic wound healing through multiple mechanisms, including ROS scavenging, bactericidal activity, anti‐inflammatory effects, and the promotion of angiogenesis. Transcriptome sequencing revealed that the HA@Cur@Ag hydrogel effectively suppressed the activation of the tumour necrosis factor (TNF)/ nuclear factor κB (NF‐κB) pathway to ameliorate oxidative stress and inflammation in diabetic wounds. These findings suggested that this ROS‐responsive multifunctional injectable hydrogel, which possessed the ability to precisely coordinate and integrate intricate biological and molecular processes involved in wound healing, exhibited notable potential for expediting diabetic wound healing.This article is protected by copyright. All rights reserved

show abstract

Hyaluronic Acid‐Based Reactive Oxygen Species‐Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing

Shi,

Zhang,

et al. 2023

Adv Healthcare Materials

View full text Add to dashboard Cite

show abstract

The Temporal Changes in Ankle Joint Pathology, Pain and Secondary Osteoporosis in Collagen-Induced Arthritis Rats

Liu,

Nan,

et al. 2024

JIR

View full text Add to dashboard Cite

Advanced application of metal nanoparticles in the diagnosis and treatment of rheumatoid arthritis

Zhang,

Xu,

Chen

et al. 2025

Polyoxometalates

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Ångstrom-scale silver particles ameliorate collagen-induced and K/BxN-transfer arthritis in mice via the suppression of inflammation and osteoclastogenesis

Cited by 3 publications

References 45 publications

Hyaluronic Acid‐Based Reactive Oxygen Species‐Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing

Hyaluronic Acid‐Based Reactive Oxygen Species‐Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing

The Temporal Changes in Ankle Joint Pathology, Pain and Secondary Osteoporosis in Collagen-Induced Arthritis Rats

Advanced application of metal nanoparticles in the diagnosis and treatment of rheumatoid arthritis

Contact Info

Product

Resources

About