1960
DOI: 10.1016/s0140-6736(60)91264-2
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Anhidrosis Following Intravenous Bacterial Pyrogen

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1964
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Cited by 26 publications
(10 citation statements)
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“…This is shown by the aforementioned observations of Bannister (25) and also by studies, currently in progress, described by Wolff, Rubenstein, and Mulholland (35). Fever was induced in volunteers by a series of injections of the pyrogenic adrenal steroid etiocholanolone.…”
Section: Discussionsupporting
confidence: 55%
See 1 more Smart Citation
“…This is shown by the aforementioned observations of Bannister (25) and also by studies, currently in progress, described by Wolff, Rubenstein, and Mulholland (35). Fever was induced in volunteers by a series of injections of the pyrogenic adrenal steroid etiocholanolone.…”
Section: Discussionsupporting
confidence: 55%
“…An effect of induced fever that may be pertinent has been observed by Bannister (25) There is evidence that induced fever in man potentiates the effects of small doses of endotoxin. This is shown by the aforementioned observations of Bannister (25) and also by studies, currently in progress, described by Wolff, Rubenstein, and Mulholland (35).…”
Section: Discussionmentioning
confidence: 88%
“…The unaltered pyrogenic responses to endotoxin in control subjects infected with the virus of sandfly fever provide additional evidence to exclude nonspecific effects of infection or fever per se. The absence of augmented pyrogenic reactivity to endotoxin during fever induced by a hot environment, as mentioned previously (17,18), is also consistent with this thesis. c) Augmented pyrogenic responses occurred regardless of whether a high degree of tolerance to the endotoxin was induced before infection by repeated daily intravenous injections or whether only a single control intravenous base-line test was performed.…”
Section: Resultssupporting
confidence: 90%
“…We emphasize that a real augmentation of pyrogenic responsiveness to endotoxin occurs during illness in that the increments in body temperature were consistently greater in both rate and magnitude, and usually duration, i.e., fever indexes were higher than those seen during the control period. This is in sharp distinction to observations by Bannister in man (17) and by Atwood and Kass in rabbits (18), wherein the injection of endotoxin during fever induced by exposure to a hot environment led to increments in body temperature (rate, magnitude, and duration) no greater than those seen under normal environmental conditions. Although body temperatures after endotoxin were higher in the hot environment, the initial temperatures were correspondingly elevated; these reactions represent additive rather than hyperreactive pyrogenic responses to endotoxin.…”
Section: Resultscontrasting
confidence: 51%
“…These data have usually been interpreted as substantiating the view that fever represents a rise in the set-point of T c . In the design in which pyrogens were administered during heat exposure after T c had stabilized (Bannister 1960;Lipton and Kennedy 1979), the results were cessation of sweating or panting, cutaneous vasoconstriction and hyperthermogenesis, usually in that order. The latencies, magnitudes and durations of the fevers produced were similar for a given dose in neutral and warm environments, but the maximum T c reached was higher in the latter since it started from an already elevated level.…”
Section: Discussionmentioning
confidence: 99%