Aniba canelilla (Kunth) Mez (Lauraceae): A Review of Ethnobotany, Phytochemical, Antioxidant, Anti-Inflammatory, Cardiovascular, and Neurological Properties

Abstract

Aniba canelilla (Kunth) Mez, popularly known as "casca preciosa" (precious bark), falsa canela (cinnamon-scented) Casca-do-maranhão (bark of maranhão), and Folha-preciosa (precious leaf), is an aromatic species of the Lauraceae family, widely distributed in the Amazon region. In traditional medicine, it is indicated for the treatment of a great diversity of diseases, including digestive, respiratory, inflam]matory, painful, and central nervous system disorders, it is administered mainly in the form of tea or decoction orally. Its essential oil is referred to as a natural antioxidant for food preservation and disease control, showing great potential for use in the cosmetics, perfumery, and pharmaceutical products sector. The present review aimed to discuss critically and comprehensively the ethnobotanical characteristics, phytochemical constitution, and scientifically tested biological properties of A. canelilla, systematizing the knowledge about the species and proposing new perspectives for research and development. The chemical composition of A. canelilla includes 1-nitro-2-phenylethane, metyleugenol, eugenol, safrol, anabasin, anbin, tannin, a-pinene, b-pinene, b-felandren, b-caryophyllene, b-sesquifelandren, p-cymene, linalool, a-copaene, and spatulenol. Researches with ethanolic extracts, essential oils, and major constituents (1-nitro-2-phenylethane and metyleugenol) have revealed antioxidant, antinociceptive, anti-inflammatory, cardio-modulating, hypotensive (vasorelaxant), hypnotic, anxiolytic, anticholinesterase, and antibiotic properties (trypanomicidal, leishmanicidal, and antifungal). Some of these effects are potentially beneficial for aging-related diseases treatment, such as cardio and cerebrovascular,

Doença de alzheimer: atividade anticolinesterásica das plantas alimentícias não convencionais (PANC) uma revisão integrativa narrativa

“…Aniba canelilla (Kunth) Mez, pertente à família da (Lauraceae) é uma planta aromática alimentícia não convencional (Kinupp & Lorenzi, 2014) conhecida popularmente por casca preciosa, falsa canela, casca-do-maranhão e folha-preciosa dentro outros nomes, seu aroma semelhante à canela, seus galhos, cascas e folhas são utilizados na culinária, essa espécie possui crescimento variável devido condições ambientais, pode possui cerca de 10 a 50 metros de altura, tem despertado interesse pela indústria farmacêutica devido a presença dos metabolitos secundários tal com taninos, flavonoides e alcaloides e propriedades medicinais em processos inflamatórios, dolorosos, sistema nervoso central, analgésica, cosméticas, antidepressiva, anticonvulsivo, antimicrobiano (Kreutz et al, 2021;Souza-Junior et al, 2020).…”

Ethnobotanical inventory of medicinal plants used by specialists in the treatment and cure of diseases in riverside communities in the amazon

“…It is mainly administered as tea. Its essential oil is a natural antioxidant for preserving food and controlling disease, displaying great potential for use in the cosmetics, perfumery and pharmaceutical products sectors [53] . Rural populations, such as those in the Resex communities, in the face of diseases, initially use medicinal plants in primary health care.…”

Lipase production from Aniba canelilla endophytic fungi, characterization and application of the enzymatic extract

“…It has been used by Amazonian traditional medicine for the treatment of pain and digestive, respiratory, inflammatory, and central nervous system disorders. Its ethanolic extracts present phenolic compounds, tannins, flavonoids, saponins, and its essential oil may contain up to 90% 1-nitro-2-phenylethane, a substance that presents several pharmaceutical properties, such as antifungal, antinociceptive, hypnotic, anticonvulsant, anxiolytic and cytotoxic activities (Barros et al, 2018;Souza-Junior et al, 2020).…”