2022
DOI: 10.1002/jnr.25120
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Animal models of compression spinal cord injury

Abstract: Compression spinal cord injuries are a common cause of morbidity in people who experience a spinal cord injury (SCI). Either as a by‐product of a traumatic injury or due to nontraumatic conditions such as cervical myelitis, compression injuries are growing in prevalence clinically and many attempts of animal replication have been described within the literature. These models, however, often focus on the traumatic side of injury or mimic short‐term injuries that are not representative of the majority of compres… Show more

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Cited by 12 publications
(12 citation statements)
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“…Clinically, compression injuries are becoming more common, and numerous efforts at animal model replication indicative of the specific clinical cases have been documented in the literature. 30 For previous syringomyelia animal models, 31 , 32 , 33 the commonality lies mainly in that CC could expand as a result of increased turbulence that prompted CSF flow to the CC through the perivascular spaces (Virchow-Robin space). At this point, it seems to be consistent with the effect of our animal model.…”
Section: Discussionmentioning
confidence: 99%
“…Clinically, compression injuries are becoming more common, and numerous efforts at animal model replication indicative of the specific clinical cases have been documented in the literature. 30 For previous syringomyelia animal models, 31 , 32 , 33 the commonality lies mainly in that CC could expand as a result of increased turbulence that prompted CSF flow to the CC through the perivascular spaces (Virchow-Robin space). At this point, it seems to be consistent with the effect of our animal model.…”
Section: Discussionmentioning
confidence: 99%
“…In the lumbosacral region, it causes psoas abscess formation. 8,9 Surgical technique varies depending on the location of the lesion. In the cervical region, mostly anterior trans-cervical approach was used with decompression of the vertebral bodies and discs.…”
Section: Discussionmentioning
confidence: 99%
“…These were the age of patients, bladder involvement, spasticity, and duration of neurological involvement. 5,9 First of all, patients were considered according to the age of the patient. Various studies have been done on this topic.…”
Section: Discussionmentioning
confidence: 99%
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