A study of the intensity distribution of the earthquake of December 5th 1456, which affected a large area of central and southern Italy was carried out, verifying, through a recently proposed methodology, the two hypotheses assumed by different authors for one single seismic event and three distinct and close ones. This methodology is based on a vectorial modelling of the macroseismic intensity distribution which aims at determining the epicentre and the principal (minimum and maximum) attenuation directions.The study was structured, considering each of the two assumed hypotheses, in a set of tests obtained for the macroseismic field and the intensity map, by analysing different configurations of the observed intensity distribution.The results obtained are in agreement with the hypothesis of the time coexistence of three distinct seismic events, for which the calculated epicentres and the principal attenuation directions are compatible with the observed intensity distribution and with the tectonic trend of the Apennine region, respectively.