Ankyloblepharon filiforme adnatum

JAIN, S.; ATKINSON, A. J; Hopkisson, B

doi:10.1136/bjo.81.8.705d

Cited by 24 publications

(13 citation statements)

References 4 publications

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“…Here, we present two newborns with AFA who were treated successfully by separation of the eyelids. Case reports are rare in the literature with or without other associated congenital abnormalities 23456789…”

Section: Introductionmentioning

confidence: 99%

Ankyloblepharon filiforme adnatum: Report of two cases

Chakraborti

Chaudhury

Das

et al. 2014

Middle East Afr J Ophthalmol

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Ankyloblepharon filiforme adnatum (AFA) is a rare congenital anomaly characterized by partial or complete adhesion of upper and lower eyelids, usually seen as an isolated finding but often associated with other anomalies or a well-defined syndrome. We report two cases of AFA who presented at a tertiary eye care center of West Bengal. Family history of consanguinity was absent. One baby had abnormal tuft of hair over the small of the back. No other congenital abnormalities were detected in any of them. The adhesions of the eyelids were divided by a number 15 blade after crushing with mosquito forceps in both cases without any anesthesia. Subsequent ocular examinations following separation and during follow-up revealed normal eyelid function, ocular motility, and fundus. In a case of AFA, timely separation of the eyelids is crucial to avoid the development of occlusion amblyopia. Cases of AFA reported in the literature are reviewed.

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Section: Introductionmentioning

confidence: 99%

Ankyloblepharon filiforme adnatum: Report of two cases

Chakraborti

Chaudhury

Das

et al. 2014

Middle East Afr J Ophthalmol

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“…AFA may be associated with a popliteal pterygium syndrome (PPS, characterized by intercrural webbing of the lower limbs) [7], CHANDS (curly hair -ankyloblepha-ron -nail dysplasia syndrome) [8], hydrocephalus, meningomyelocele, imperforate anus [11], cardiac problems such as ductus arteriosus and ventricular septal defects [7], a cleft lip and/or palate [9,19], or with skin hypopigmentation in the absence of cleft lip/palate [10]. AFA can be seen in trisomy 18 (Edwards syndrome) [1,2,5,14,17], as a part of Hay-Wells syndrome [4,6,18,24,25,26], or in both syndromes together [17].…”

Section: Discussionmentioning

confidence: 99%

“…It was first described by Josef von Hasner in 1881 [1]. AFA occurs sporadically and has an incidence of 4.4 cases per 100,000 births [2,3,4]. Although this anomaly has been reported as an isolated anomaly, it may also be found in association with other anomalies or as a part of well-defined syndromes such as Edward's syndrome, Hay-Wells syndrome, etc.…”

Section: Introductionmentioning

confidence: 99%

Ankyloblepharon Filiforme Adnatum with a bilateral cleft lip and palate

2018

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Introduction Ankyloblepharon filiforme adnatum (AFA) is a rare congenital abnormality of the eyelids that has been reported as an isolated anomaly, but may also be associated with other anomalies or as a part of well-defined syndromes. The aim of this work was to present a case of familial AFA associated with bilateral cleft lip and palate. Case outline A full-term female newborn (40 weeks' GA, BM 3,700 g) had bilateral partially fused eyelids at birth, associated with a cleft lip and palate. The surgical treatment was performed five days after AFA was diagnosed. The baby's mother also had AFA, without a cleft lip or palate. The baby girl has been followedup by a plastic surgeon, a specialist in orthodontics, as well as an ophthalmologist and a pediatrician. Conclusion This case indicates familial clustering of AFA, whereby it assumes a more severe form in the following generation. A cleft lip and palate in our patient has required surgical treatment, oral and dental rehabilitation, as well as the need for more intensive care and regular follow-ups by multidisciplinary teams.

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“…AFA was first described by Josef von Hasner in 1881, and is characterised by partial or complete adhesion of the ciliary edges of the upper and lower eyelids. 2 Usually, AFA constitutes a solitary malformation of sporadic occurrence. However, it may also occur in an autosomal dominant pattern associated with cleft lip and cleft palate.…”

Section: Discussionmentioning

confidence: 99%