Ankylosing Spondylitis in Women

Fd, Hart; Kc, Robinson

doi:10.1136/ard.18.1.15

Cited by 53 publications

(21 citation statements)

References 4 publications

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“…The precise ratio is less important than the fact that AS does occur in women and should be included in the differential diagnosis of back pain. Even so it can be difficult to reach a definite diagnosis as the clinical and radiographic evolution is often slower than in men (Tyson, Thompson, and Ragan, 1953;Hart and Robinson, 1959). A strong positive association exists between the histocompatibility antigen HLA-B27 (formerly W27) and AS in men and predominantly male mixed samples, at least 88 % of patients belonging to this tissue type (Brewerton and others, 1973;Schlosstein and others, 1973).…”

mentioning

confidence: 99%

Clinical diagnosis of ankylosing spondylitis in women and relation to presence of HLA-B27.

Hill¹,

Hill²,

Bodmer³

1976

Annals of the Rheumatic Diseases

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. (1976). Annals ofthe Rheumatic Diseases, 35,[267][268][269][270]. Clinical diagnosis of ankylosing spondylitis in women and relation to presence ofHLA-B27. Thirty-nine Caucasian women with definite or probable ankylosing spondylitis were tissue typed and the radiographic and clinical features were correlated with the presence of B27 (formerly W27). This investigation showed that the same strong positive correlation observed in men obtains in women between B27 and unequivocal radiographic changes. As such changes develop slowly in women, clinical and laboratory features were identified which were sufficiently characteristic to enable the diagnosis to be reached in advance of decreased spinal mobility. Immobility pain and stiffness and bilateral sacroiliac pain are the most characteristic features, but additional support is provided by the presence of any of the following: onset by age 30, a raised sedimentation rate, peripheral joint involvement, circumthoracic pain, family history, and iritis.

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mentioning

confidence: 99%

Clinical diagnosis of ankylosing spondylitis in women and relation to presence of HLA-B27.

Hill¹,

Hill²,

Bodmer³

1976

Annals of the Rheumatic Diseases

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“…Six patients, all women, had bilateral hip ankylosis (fusion) without femoral head deformity. Osteophytic and cystic changes were strikingly absent from this group, which appears to be a distinct radiographic entity not previously described as a feature of female spondylitis (Tyson et al 1953;Hart and Robinson, 1959;Hill et al, 1976;Resnick et al, 1976). These 6 patients were indistinguishable from the other female patients in the series as regards the onset of spondylitis and hip symptoms, the involvement of other peripheral joints, and previous treatment.…”

Section: Discussionmentioning

confidence: 45%

Clinical and radiographic features of spondylitic hip disease.

Marks¹,

Hardinge²

1979

Annals of the Rheumatic Diseases

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“…These features are similar to those seen in rheumatoid arthritis and are the basis for the current opinion that ankylosing spondylitis is a variant of rheumatoid arthritis' (Cruickshank, 1951). The same author, writing in 1960, made no fundamental changes to these views of the histopathology of the disease, a description which accords in general with that of other authors (Rutishauser and Jacqueline, 1955). Bywaters (1968) described the joint pathology in a patient who died in the pre-ankylosing stage of the disease.…”

mentioning

confidence: 76%