Tin oxide (SnO2) nanoparticles have been synthesized via microwave-assisted solution method. The structural analysis was carried out using X-ray diffraction. It showed that the SnO2 nanoparticle exhibited primitive tetragonal structure. The SnO2 product was investigated by FT-IR, UV, SEM and antimicrobial activity studies of SnO2 have confirmed that they have biomedical applications.