2019
DOI: 10.31234/osf.io/dp5nf
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Annual variation in attentional response after Methylphenidate treatment

Abstract: Prevalence rates of Attention-Deficit/Hyperactivity Disorder (ADHD) differ with geographical areas varying in sunlight intensity. We here studied 1) annual variation in inattention at treatment initiation; 2) annual variation in response to ADHD treatment [Methylphenidate (MPH)] by day of treatment initiation; and 3) dose-dependency. We predicted least baseline inattention during a period of high sunlight intensity implying more room for improvement (i.e., a better treatment response) when sunlight intensity i… Show more

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“…of DRD4 on central nervous system level cannot be ruled out at this time. We earlier also observed a lack of circannual pattern in inattention using non-genotyped data, expectedly consisting mainly of 7R-non-carriers (58). Surprisingly, 7R-carriers did not increase to a normal level after winter solstice, but to a level better than 7R-non-carriers.…”
Section: Discussionmentioning
confidence: 65%
“…of DRD4 on central nervous system level cannot be ruled out at this time. We earlier also observed a lack of circannual pattern in inattention using non-genotyped data, expectedly consisting mainly of 7R-non-carriers (58). Surprisingly, 7R-carriers did not increase to a normal level after winter solstice, but to a level better than 7R-non-carriers.…”
Section: Discussionmentioning
confidence: 65%