This paper employs a scoping review methodology to thoroughly investigate the distinctive challenges and opportunities that define digital transformation in African organizations. By examining critical dimensions, including technological infrastructure, governmental commitment, organizational culture, human capital development, regulatory environments, market dynamics, and economic factors, the study provides an in-depth analysis against the backdrop of Africa's burgeoning economies and the transformative aftermath of COVID-19. The scoping review methodology facilitates a comprehensive and expansive approach to literature examination, aligning key variables and essential terms with relevant literature sources. Drawing insights from a diverse range of materials, the findings illuminate both the transformative potential of digital technologies in Africa and the persistent hurdles, such as the digital divide, skills shortages, and infrastructure deficits. The synthesis of these insights not only underscores the imperative for innovation and widespread adoption but also emphasizes the necessity of societal restructuring to fully realize the impact of digital technologies in Africa. In conclusion, the paper offers recommendations that advocate for holistic, collaborative solutions, bringing together governments, private entities, and educational institutions in strategic alignment with the global discourse on Africa's role in the digital economy.