A 56-year-old male patient was admitted for catheter ablation of highly symptomatic paroxysmal atrial fibrillation. During the procedure, a rare anatomic variation with an interrupted inferior caval vein (ICV) branching suprarenal into an azygos venous continuation draining into the superior caval vein was detected. Using angiography, a continuation of the ICV leading into the liver, subdividing into 5 smaller branches draining into the right atrium (RA), was displayed. Despite this challenging anatomic variation, successful pulmonary vein isolation (PVI) was performed.
Case ReportA 56-year-old male patient was admitted for catheter ablation of highly symptomatic drug-refractory paroxysmal atrial fibrillation (2 to 3 episodes per week), first diagnosed 48 months before the procedure. Physical examination revealed no anomalous findings, and medical history was unremarkable except for a known 1-vessel coronary artery disease with status post bare metal stent implantation in the left anterior descending artery, normal left ventricular function, and left atrial (LA) diameter of 51 mm. No LA thrombus was detected before the procedure by transesophageal echocardiography. No additional preinterventional imaging was performed.
Ablation ProcedureAfter written informed consent was obtained, the procedure was performed under conscious sedation using boli of midazolam, fentanyl, and a continuous infusion of propofol (1%). Venous accesses (8F) were achieved via the right femoral vein, the left femoral vein, and the left subclavian vein. Positioning of both deflectable diagnostic catheters (7F, Webster, Biosense Webster, Diamond Bar, Calif) in the coronary sinus from the left subclavian vein and at the Hisbundle region via the left femoral vein was unremarkable.
Transseptal PunctureThe guide wire for the first transseptal sheath was introduced via the right femoral vein. The guide wire exhibited an uncommon course and did not enter the RA from inferior; angiography revealed a persistent vena azygos draining into the superior caval vein (Figure 1). An additional angiography from the ICV demonstrated suprarenal branching into an azygos vein and, as another exceptional anatomic variant, a continuation of the ICV leading to the liver vein, which subdivided into 5 branches directly entering the RA (Figure 1).Intending to minimize the periprocedural risk with regard to the challenging transseptal puncture (TP) in this unique anatomic setting, we decided to perform cryoballoon-based PVI using only a single TP. Moreover, the steerable sheath (12F, FlexCath, CryoCath, Montreal, Canada), which is used in combination with the cryoballoon system, allows complex movements within the LA and ascertains access to all PVs.The guide wire was advanced via the ICV continuation to the most medial liver vein branch (Figure 1) into the RA, providing best access to the fossa ovalis. The steerable sheath was advanced and TP was performed with pressure monitoring in standard right anterior oblique (RAO) 30°and left anterior oblique (LAO) 40°angulation...