Encyclopedia of Life Sciences 2017
DOI: 10.1002/9780470015902.a0026852
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Anophthalmia/Microphthalmia/Coloboma ( MAC )

Abstract: Microphthalmia/anophthalmia/coloboma (MAC) are congenital anomalies of the eye that form a continuum from coloboma at the mild end to anophthalmia at the severe end. When we refer to anophthalmia, usually we mean clinical anophthalmia where there is so little eye tissue that it is not visible, but it is in fact severe microphthalmia. On magnetic resonance imaging (MRI) of the orbit, rudimentary tissue might be visible and in some cases, you can see a hypoplastic optic nerve. There may be eye adnexa present lik… Show more

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