Anorexia nervosa and reproduction: connecting brain to gonads

Poterasu, Mihaela; Rowland, David L.; Ciobanu, C; Fica, Simona

doi:10.22543/7674.71.p18

Cited by 1 publication

(1 citation statement)

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“…This protection may be provided by directing energy away from non-critical bodily functions, such as reproduction, especially in females. For example, in humans, menses is delayed or paused as a result of low energy stores, known as anorexic amenorrhea [ 36 , 72 ]. However, this ability to allocate energy resources may extend beyond moments of extreme physiological distress.…”

Section: Introductionmentioning

confidence: 99%

Sex differences and sex-specific regulation of motivated behavior by Melanin-concentrating hormone: a short review

Kuebler,

Suárez,

Wakabayashi

2024

Biol Sex Differ

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Recent preclinical research exploring how neuropeptide transmitter systems regulate motivated behavior reveal the increasing importance of sex as a critical biological variable. Neuropeptide systems and their central circuits both contribute to sex differences in a range of motivated behaviors and regulate sex-specific behaviors. In this short review, we explore the current research of how sex as a biological variable influences several distinct motivated behaviors that are modulated by the melanin-concentrating hormone (MCH) neuropeptide system. First, we review how MCH regulates feeding behavior within the context of energy homeostasis differently between male and female rodents. Then, we focus on MCH’s role in lactation as a sex-specific process within the context of energy homeostasis. Next, we discuss the sex-specific effects of MCH on maternal behavior. Finally, we summarize the role of MCH in drug-motivated behaviors. While these topics are traditionally investigated from different scientific perspectives, in this short review we discuss how these behaviors share commonalities within the larger context of motivated behaviors, and that sex differences discovered in one area of research may impact our understanding in another. Overall, our review highlights the need for further research into how sex differences in energy regulation associated with reproduction and parental care contribute to regulating motivated behaviors.

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Section: Introductionmentioning

confidence: 99%