Antagonistic Activity of Agaricuscampestris mushroom Extracts Against some Human Pathogenic Bacterial Species

Abstract

The present study focused on the evaluation of Agaricuscampestris mushroom extracts activity against four clinical isolates Escherichia coli; Pseudomonas aerginosa; Staphylococcus haemolyticus and Staphylococcus aureus. Agaricuscampestris mushroom extracts varied in their antimicrobial activity. The intensity of the antimicrobial effect is dependent upon the solvent , concentration of the mushroom extract and the organism being tested against .Therefore, The hot water and ethanolic extract 96%showed maximum inhibition at high concentrations specially at 500 mg/ml concentration( 17, 16, 19, 16 ) mm and ( 20,21,19,20) against E. coli , Pseudomonas aerginosa; Staphylococcus aureus and Staphylococcus haemolyticus respectively compared with methanolic extract . The ethyl acetate extract of the powder mushroom of Agaricuscampestris was analyzed to 9 chemical compounds belonged to fatty acids and their derivatives and included :-Nonadecane, Pentacosane, Octadecane, Heptadecane, Heneicosane, Hexadecane, 2,6,10,14-tetramethyl, Butanoic acid, 3,7-dimethyl-6-octenyl ester, Phthalic acid mono-2-ethylhexyl ester ,, Octanoic acid, heptadecyl ester.