The size selectivity of trammel nets was investigated in the northern Aegean Sea using 10 different inner-panel mesh sizes ranging from 16 to 70 mm nominal mesh size (bar length). Selectivity estimates were made for the eight most abundant target and bycatch fish species, namely black scorpionfish, Scorpaena porcus Linnaeus, 1758; annular seabream, Diplodus annularis (Linnaeus, 1758); red mullet, Mullus barbatus Linnaeus, 1758; surmullet, Mullus surmuletus Linnaeus, 1758; round sardinella, Sardinella aurita Valenciennes, 1847; European hake, Merluccius merluccius (Linnaeus, 1758); greater weever, Trachinus draco Linnaeus, 1758; and blotched picarel, Spicara flexuosum Rafinesque, 1810, which accounted for 51.5% by number and 42.7% by weight of the fish caught with trammel nets in the sea trials. The SELECT method was used to estimate the selectivity parameters. Five different selectivity functions (i.e., normal scale, normal location, gamma, log-normal, and bi-normal) were applied with the bi-normal function providing the best fit as it had the lowest deviance value for all species and the lowest values for the dispersion parameter (D/df). The mesh size of 16 mm in most of the cases retained specimens below the size at first maturity (Lm). The mesh size of 19 mm seems more appropriate for red mullet, surmullet, and blotched picarel, the mesh size of 22 mm for annular seabream and round sardinella, while for European hake and black scorpionfish, the mesh size larger than 26 mm would be more appropriate.