Antecollis in Parkinsonism

Jorens, P. G.; Eycken, MichelP.; Parizel, G; Martin, J. J.

doi:10.1016/s0140-6736(89)92706-2

Cited by 30 publications

(21 citation statements)

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“…Jorens et al [7] reported a patient with PD in whom dropped head was improved by treatment with levodopa. We experienced a similar case [14] and Horiuchi et al [5] also reported such a case.…”

Section: Dopamine Agonists and Dropped Headmentioning

confidence: 99%

Dropped head in Parkinson’s disease

Fujimoto

2006

J Neurol

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"A propensity to bend the trunk forward" and "the chin is now almost immovably bent down upon the sternum" were described by James Parkinson in patients with Parkinson's disease (PD). The term "dropped head" was first reported in "Gerlier disease" in Switzerland and 'kubisagari' in Japan and since then also reported in myositis, myopathy, myasthenia gravis, amyotrophic lateral sclerosis, neuropathy, and hypothyroidism. Disproportionate antecollis occurs in about half cases of multiple system atrophy (MSA) and is considered dystonic in nature. Dropped head is considered rare in PD, both in advanced and early stages of PD. However, it is known to progress subacutely over a period of several days. In my experience, dropped head is relatively common in PD. The mechanism of dropped head in PD is either dystonia of flexor neck muscles or weakness of extensor neck muscles. The response of dropped head to various anti-parkinsonian medications is rather inconsistent. Levodopa is reported to induce amelioration in some patients while dopamine agonists can cause deterioration. Muscle afferent block with lidocaine and ethanol is reported to be effective, while the effect of botulinum toxin injection into the affected muscles is limited. The effect of stereotaxic neurosurgery on dropped head is controversial. Early diagnosis and prompt treatment is necessary to prevent muscle damage associated with longterm overstretch of extensor neck muscles.

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Section: Dopamine Agonists and Dropped Headmentioning

confidence: 99%

Dropped head in Parkinson’s disease

Fujimoto

2006

J Neurol

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“…Parkinson's disease and dementia (PDD), and dementia with Lewy Bodies (DLB) are disorders that are pathologically characterized by widespread Lewy body neuronal inclusions 1. Cervical dystonia may occur in patients with Parkinson's disease (PD), although its presence often suggests the possibility of multiple system atrophy (MSA) 2–4. The incidence of cervical dystonia in PDD is unknown, but to our knowledge, only 2 such patients have been reported previously 5.…”

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confidence: 99%

Severe cervical dystonia in pathologically proven Parkinson's disease and dementia (PDD)

Cohen

Fahn

2003

Movement Disorders

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“…Our first Patient presented with a "dropped head" [3]. This pattern of neck muscle weakness has been described in various conditions including movement disorders, neuromuscular diseases, motor neuron and muscle diseases.…”

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confidence: 89%