Background: Abortion-related complications are one of the five main causes of maternal mortality. However, research about abortion is very limited in fragile and conflict-affected settings. Our study aims to describe the magnitude and severity of abortion-related complications in two referral hospitals located in such settings in northern Nigeria and Central African Republic (CAR).Methods: We used a methodology similar to the World Health Organization (WHO) near-miss approach adapted in the WHO multi-country study on abortion (WHO-MCS-A). We conducted a cross-sectional study using prospective medical record review of women presenting with abortion-related complications between November 2019 and July 2021. We used descriptive analysis and categorized complications into four mutually exclusive categories of increasing severity.Results: We analyzed data from 520 women in Nigeria and 548 women in CAR. Abortion complications represented 4.2% (Nigeria) and 19.9% (CAR) of all pregnancy-related admissions. The severity of abortion complications was high: 103 (19.8%) and 34 (6.2%) women were classified as having severe maternal outcomes (near-miss cases and deaths), 245 (47.1%) and 244 (44.5%) potentially life-threatening, 39 (7.5%) and 93 (17.0%) moderate, and 133 (25.6%) and 177 (32.3%) mild complications, respectively in Nigeria and CAR. Severe bleeding/hemorrhage was the main type of complication in both settings (71.9%in Nigeria, 57.8% in CAR), followed by infection (18.7% in Nigeria, 27.0% in CAR). Among the 146 women (Nigeria) and 231 women (CAR) who did not report severe bleeding or hemorrhage before or during admission, anemia was more frequent in Nigeria (66.7%) compared to CAR (37.6%).Conclusion: Our data suggests greater severity of abortion-related complications compared with the 210 African referral facilities of a recent WHO study in more stable settings. Factors that could contribute to this greater severity in these contexts include greater delays in accessing post-abortion care, decreased access to contraceptive and safe abortion care that result in increased unsafe induced abortions; as well as increased food insecurity leading to iron-deficiencies and chronic anaemia. The results highlight the need for better access to safe abortion care, contraception, and high quality postabortion care to prevent and manage complications of abortions in fragile and conflict-affected settings.