Anterior and Posterior Mediastinum Leiomyomas Arising From the Parietal Pleura

Torres-Luna, Jonathan; Mercader-Pérez, Mariana; Magno, Priscilla; Rodríguez-Cintrón, William

doi:10.1016/j.athoracsur.2019.07.082

Cited by 1 publication

(3 citation statements)

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“…Preliminary diagnosis is enhanced by a chest CT defining the mass (solitary, well-circumscribed tumor with heterogeneous density), size, location, blood supply and its relation to the adjacent vital mediastinal organs [ 3 , 5 ]. Some tumors can develop degenerative changes such as hemorrhage, cystic changes and calcifications [ 6 ]. Based on the findings and age of the patient, pleuropulmonary blastoma and neurogenic tumor (ganglioneuroma) may be considered for differential diagnoses.…”

Section: Discussionmentioning

confidence: 99%

“…The definitive diagnosis is achieved by histology. Microscopically, leiomyoma consists of monomorphic spindle cells with blunt-ended nuclei, arranged in interlacing fascicles, without atypia, mitosis or necrosis [ 4 , 6 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

“…In case of recurrence, leiomyosarcoma should be considered [ 4 ]. Leiomyoma is often considered as benign tumor with a low malignant potential; however, there is need for strict follow-up because of reported metastasis [ 3 , 6 , 8 ].…”

Section: Discussionmentioning

confidence: 99%

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Ectopic uterus? A rare presentation of a giant leiomyoma in the posterior mediastinum

Tarmohamed

Mashambo

Sadiq

et al. 2021

Journal of Surgical Case Reports

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Leiomyomas are benign mesenchymal tumors derived from smooth muscles. Uterus is the commonest site of origin for leiomyomas; however, unusual growth patterns and locations have been reported posing diagnostic challenges, clinically and radiologically. Histological diagnosis remains the gold standard of diagnosis. Here, we present a 17-year-old female with a 3-month history of chest pain, cough, difficulty in breathing and chest tightness. Chest CT scan showed a 12.3 cm × 14.4 cm × 22.8 cm mass occupying the entire left posterior hemithorax. The patient underwent thoracotomy and recovered well after surgery. Histopathology of the excised specimen confirmed it to be leiomyoma. Despite its rarity, primary mediastinal leiomyoma should be considered in the differential diagnosis of an unexplained mediastinal mass. Its accurate pre-operative diagnosis is difficult. Respiratory compromise and risk of transformation to sarcoma mandate complete surgical resection for a definitive diagnosis and good prognosis.

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Section: Discussionmentioning

confidence: 99%