Anterior Chamber Depth and Chamber Angle and Their Associations with Ocular and General Parameters: The Beijing Eye Study

Xu, Liang; Cao, Weijie; Wang, Ya Xing; Chen, Chang Xi; Jonas, Jost B.

doi:10.1016/j.ajo.2008.01.004

Cited by 215 publications

(192 citation statements)

References 22 publications

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“…Previous studies have found that people with hypermetropia are at greater risk for angle closure. 10,20,24 In our study, the mean refraction of the control, PAC, and PACG groups were À 0.23D, þ 0.86D, and þ 0.29D, respectively, suggesting that our PAC was more hypermetropic than the control group (Po0.001). We did not find trend toward hypermetropia between the PAC and PACG group.…”

Section: Discussionmentioning

confidence: 83%

“…Several studies have investigated the relationship between stature and ocular dimension. [20][21][22] The Beijing Eye study reported a significant association between a shallow ACD and a narrow anterior chamber angle and short body stature. 20 The Singapore Malay Eye study reported an association between longer AXL and greater body height.…”

Section: Discussionmentioning

confidence: 99%

“…[20][21][22] The Beijing Eye study reported a significant association between a shallow ACD and a narrow anterior chamber angle and short body stature. 20 The Singapore Malay Eye study reported an association between longer AXL and greater body height. 22 The Tanjong Pagar survey in Singapore also reported a significant association between 21 Thus, a shorter person may have smaller eyes, which might predispose them to angle closure.…”

Section: Discussionmentioning

confidence: 99%

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The biometric study in different stages of primary angle-closure glaucoma

Chen

Sj²,

Chou³

2013

Eye

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Purpose This study compared the general and ocular biometric characteristics of normal, primary angle closure (PAC), and primary angle-closure glaucoma (PACG) patients to better understand the possible relationship between differences in ocular parameters that might predict risk for PACG in PAC patients. Methods One hundred normal, 90 PAC, and 90 PACG eyes were retrospectively reviewed. General characteristics such as age, gender, body height, body weight, blood pressure, pulse, systemic diseases, and education level were recorded. Ocular findings included visual acuity, intraocular pressure, refraction, cup to disc ratio, and ocular biometry. Ocular biometry was obtained by A-scan ultrasonography (Digital A/B scan 5500; Sonomed Inc.). The parameters recorded were anterior chamber depth (ACD), lens thickness (LT), axial length (AXL), lens/axial length factor (LAF), and relative lens position (RLP). Results Although the controls, PAC group, and PACG group were found to be significantly different in age (62.7 ± 9.8; 65.3 ± 7.5; and 66.0 ± 7.4, respectively), there were no gender differences. With regard to ocular parameters, the ACD tended to decrease and the LT and LAF tended to increase from normal to PAC to PACG. The eyes of the PACG group had significantly shallower ACD (Po0.001) and thicker lens (Po0.001) than those of the PAC group. While PAC had similar lens position to the control group, PACG had more anteriorly positioned lens than the PAC group (Po0.001). Logistic regression analysis found a significant association between a decrease in ACD and increased risk of PACG (odds ratio (OR) ¼ 3.59 for 0.2 mm decrease in ACD) as well as a significant association between an increase in LT and increased risk of PACG (OR ¼ 1.30). Conclusions In addition to LT, a shallower ACD owing to a change in RLP may have a role in the progression from PAC to PACG. Owing to the differences of certain biometric characteristics between PAC and PACG, A-scan ultrasonography might potentially be used for the early detection of PACG in PAC eyes.

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Section: Discussionmentioning

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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The biometric study in different stages of primary angle-closure glaucoma

Chen

Sj²,

Chou³

2013

Eye

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“…As it use an infrared light, pupil doesn't close by providing a more natural image of angle structures without modifying their anatomy. Measurement software can be used to calculate the depth of the angle in degrees (Boyd S et al) Age and refractive error were found to be associated with anterior chamber angle measurement; one may argue that some adjustment would be required since the objective of the study was to provide population normative data (Xu L 2008).…”

Section: Fig 1 Oct Image Of the Anterior Chambermentioning

confidence: 99%

“…There are factors that have been recognized as affecting the anterior chamber angle width include age, race/ethnicity, iris color, eye dominance, corneal curvature and refraction, and illumination open or narrow angles may become closed in dark lighting conditions, which can lead to the diagnosis of angle-closure glaucoma being missed (Liu L 2008). Since the clinical introduction of the slitlamp into ophthalmology by Vogt, the dimensions of the anterior segment of the eye have usually been estimated by slit-lamp-supported biomicroscopy of the eye (Xu L 2008). Although gonioscopy is the gold standard for anterior chamber angle assessment (Baikoff G 2004, Kalev-Landoy et al 2007, Leung et al 2007, Radhakrishnan et al 2005, its inevitable need for minimal illumination to visualize the angle, the uncertainty of the change in angle configuration when a goniolens is in direct contact on the cornea, and the dependence on individual skill and experience for interpretation of the angle configuration, serve to limit its role in providing precise angle assessment.…”

Section: Introductionmentioning

confidence: 99%

Measurement of Anterior Chamber Angle with Optical Coherence Tomography

F¹,

Muñoz‐Rodríguez²,

Jl³

2011

The Mystery of Glaucoma

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Refractive Error, Axial Dimensions, and Primary Open-Angle Glaucoma

Perera¹

2010

Arch Ophthalmol

140

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To explore the relationship of refractive error and ocular biometry with primary open-angle glaucoma (POAG) in the Malay population. Methods:The Singapore Malay Eye Study is a population-based cross-sectional survey that examined 3280 persons (78.7% response) aged 40 to 80 years. Participants underwent a standardized clinical examination including slitlamp biomicroscopy, Goldmann applanation tonometry, refraction, dilated optic disc assessment, and measurement of axial length (AL) and central corneal thickness (CCT). Glaucoma was defined according to International Society for Geographical and Epidemiological Ophthalmology criteria. Results:After adjusting for possible confounders, persons with moderate or high myopia (less than −4.0 diop-ters, right eyes) were more likely to have POAG (odds ratio [OR], 2.87; 95% confidence interval, 1.09-7.53); this association remained significant after controlling for CCT (2.80; 1.07-7.37). Longer AL was associated with POAG (ORs, 2.49, 3.61, and 2.88, comparing quartiles 2, 3, and 4, respectively, with quartile 1 of AL; P=.03 for trend). If CCT was controlled for, persons with AL in quartile 4 were 3 times more likely to have POAG (OR, 3.00; 95% confidence interval, 1.09-8.24) than those in quartile 1. Conclusion:This population-based study in Singapore shows an association of moderate myopia and increasing AL with POAG independent of other factors, including CCT.

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Anterior Chamber Depth and Chamber Angle and Their Associations with Ocular and General Parameters: The Beijing Eye Study

Cited by 215 publications

References 22 publications

The biometric study in different stages of primary angle-closure glaucoma

The biometric study in different stages of primary angle-closure glaucoma

Measurement of Anterior Chamber Angle with Optical Coherence Tomography

Refractive Error, Axial Dimensions, and Primary Open-Angle Glaucoma

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