Anterior chamber gas bubbles after corneal flap creation with a femtosecond laser

Lifshitz, Tova; Levy, Jaime; Klemperer, Itamar; Levinger, Shmuel

doi:10.1016/j.jcrs.2004.12.069

Cited by 66 publications

(42 citation statements)

References 6 publications

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“…The interaction of optical radiation with biological tissue is multifaceted and, in particular, is accompanied by the occurrence of acoustic noise and the formation of bubbles (Mettin, 2007;Yusupov et al, 2014). Cavitation bubbles can effectively disinfect biological tissues, as has been reported in several studies (Lifshitz et al, 2005;Verhaagen and Rivas, 2016), so they attract special attention.…”

Section: Introductionmentioning

confidence: 98%

Control of Bubble Formation at the Optical Fiber Tip by Analyzing Ultrasound Acoustic Waves

Казаков

Yusupov

Баграташвили

et al. 2016

American Journal of Engineering and Applied Sciences

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The problems of controlling the processes of generation of acoustic waves and microbubbles at the optical fiber tip of moderatepower surgical lasers with wavelengths of 1.9 µm and 0.97 µm using active and passive acoustic methods are considered. It is shown that microbubbles of various sizes can be detected with an ultrasound method, in which the interaction area is recorded simultaneously at two frequencies. By measuring noise with a receiving transducer of an ultrasonic locator, we determine the frequency range of the acoustic signals occurring when large diameter bubbles, including gas-vapor bubbles, collapse. Model experiments are conducted to detect noise and bubbles in water and in a water-saturated 1.5% agarose phantom at various laser powers with an optical fiber tip having a strongly absorbing coating.

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Section: Introductionmentioning

confidence: 98%

Control of Bubble Formation at the Optical Fiber Tip by Analyzing Ultrasound Acoustic Waves

Казаков

Yusupov

Баграташвили

et al. 2016

American Journal of Engineering and Applied Sciences

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“…Appearance of gas bubbles in anterior chamber during flap formation with femtosecond laser has been reported in the literature [1,2]. Previously mentioned mechanisms include migration of intrastromal bubbles in the interface through peripheral corneal stroma and trabecular meshwork, or through posterior stroma and endothelium.…”

Section: Introductionmentioning

confidence: 98%

Visante® anterior segment OCT in a patient with gas bubbles in the anterior chamber after femtosecond laser corneal flap formation

2008

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A patient with anterior chamber gas bubbles after LASIK flap formation with femtosecond laser is presented. A 33-year-old male patient had LASIK for myopia with corneal flap formation with IntraLase FS30 femtosecond laser. In the right eye, air bubbles were observed in anterior chamber after successful flap formation. Laser correction was completed successfully, by Wavelight Allegretto Wave Eye-Q excimer laser, without eye-tracker. Visante anterior segment optical coherence tomography imaging displayed that the pocket extended to limbal area, with stromal bed thickness of >600 microm at that area. We propose as possible causes of the air bubbles scattering of femtosecond laser beam producing direct photodissociation of aqueous humor, or direct cavitation effect in aqueous humor due to rapid pressure changes in corneal lamellar interface during the femtosecond laser procedure. Other causes such as migration of intrastromal bubbles through peripheral corneal stroma and trabecular meshwork, or through posterior stroma and endothelium, seem to be unlikely.

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“…3,7,8 The cavitation bubbles collapse, creating powerful acoustic streaming and shock waves causing, in particular, the death of bacteria, and thereby sterilizing the wound. 9,10 Changes in tissue properties may result in nonuniform ablation followed by overheating of particular areas of the tissue and the formation of necrosis. In order to eliminate this negative factor, automatic adjustment of laser power by measuring the temperature of the optical¯ber tip is used.…”

Section: Introductionmentioning

confidence: 99%

“…[7][8][9][10][11] These methods have been developed to a considerable extent for the detection of single bubbles excited by acoustic waves at their resonant frequencies of di®erent modes of oscillation in a water. 12 Use of the above methods is well-known in relation to the detection of bubbles during decompression, or phospholipidcoated micro-bubbles in order to increase ultrasonic image contrast.…”

Section: Introductionmentioning

confidence: 99%

On the possible ultrasonic inspection of micro-bubbles generated by the optical fiber tip

Казаков

Sanin

Kamensky

2016

J. Innov. Opt. Health Sci.

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We demonstrate the possibility of detection and monitoring of bubbles emerging near the tip of an optical¯ber by means of ultrasonic method. The excitation of bubbles at their resonant frequencies is performed using short ultrasonic pulses having a wide frequency range simultaneously with their modulation by means of a long pulse of a monochromatic frequency. This method allows detection of bubbles of various sizes. Used signal processing method, which allows increased bubble detection accuracy, is proposed for research in environments of biological-like medium which show continuous variations in structure and properties when exposed to optical emission. The method has been demonstrated on model objects: in a liquid and in a biological tissue phantom using various methods of bubble generation (hydrolysis and optical emission). We studied bubble formation by the tip of a¯ber of the surgical laser LSP-007/10 \IRE Polus" with a wavelength of 0.97 m coated with a highly absorbing graphite layer.

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Anterior chamber gas bubbles after corneal flap creation with a femtosecond laser

Cited by 66 publications

References 6 publications

Control of Bubble Formation at the Optical Fiber Tip by Analyzing Ultrasound Acoustic Waves

Control of Bubble Formation at the Optical Fiber Tip by Analyzing Ultrasound Acoustic Waves

Visante® anterior segment OCT in a patient with gas bubbles in the anterior chamber after femtosecond laser corneal flap formation

On the possible ultrasonic inspection of micro-bubbles generated by the optical fiber tip

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