Anterior commissure carcinoma II: The role of salvage supracricoid laryngectomy

Rifai, Mohamed; Heiba, Mohamed; Salah, Hady

doi:10.1053/ajot.2002.28779

Cited by 20 publications

(14 citation statements)

References 14 publications

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“…5,9,17 The authors supporting surgery suggest better local control and lower relapse for T1 and T2 tumors, with different results among the various surgical techniques. 4,8,10,11 On the other hand, the supporters of radiation therapy emphasize local control similar to that obtained by surgery and better vocal quality. 5 At the Escola Paulista de Medicina, after confirming anterior commissure involvement by the tumor, open surgery was indicated in most cases, except for five cases, in which endoscopic chordectomy was performed (four T1b patients and one T2 patient).…”

Section: Discussionmentioning

confidence: 93%

“…4,[8][9][10][11] The posterior commissure was significant for total laryngectomy in glottic tumors CA: (p=0.03) and PA: (p=0.0001). It is difficult to define the posterior commissure in terms of terminology, location, and components.…”

Section: Discussionmentioning

confidence: 96%

“…The anterior commissure has important characteristics that should be taken into account in neoplasm dissemination, when approaching it surgically. [1][2][3][4][5][6][7][8][9][10][11][12] Its embryologic and anatomic formation has drawn attention of many authors, when studying laryngeal cancer dissemination. 8 These formation aspects should be pointed out to indicate the open technique in initial tumors (T1 and T2).…”

Section: Discussionmentioning

confidence: 99%

“…The main objective is tumor resection with free margins, and, consequently, local control of the disease. 2,4,[6][7][8][9][10][11][12] According to studies conducted by Rucci et al, the anterior commissure and the Broyles tendon have a clearly defined plane in which the blood vessel distribution is local, superficial, and restricted to the mucosa, with late maturation of these phonatory structures. 8,9,12 This characteristic would provide slower dissemination of the neoplasm.…”

Section: Discussionmentioning

confidence: 99%

“…1,2 The need to study the internal structures or subsites of the larynx (anterior commissure, posterior commissure, ventricle and infraglottis) since their origin, evolution, and their relation with the invasion and barrier paths to the tumor have been well documented in the literature. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] The objective of this study was to assess the laryngeal regions and subsites of 160 patients with laryngeal carcinoma, in the period between January 1998 and December 2004. Moreover, it aimed to check the proportion of affected subsites and their influence on determining conservative or radical surgery (total laryngectomy), as well as the repercussion on local control, organ preservation and survival.…”

Section: Introductionmentioning

confidence: 99%

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Fatores prognósticos no tratamento do carcinoma epidermóide da laringe: cirurgia conservadora x radical

Vidal

Cervantes

Abrahão

et al. 2007

Rev. Bras. Otorrinolaringol.

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O tratamento do carcinoma da laringe tem como desafio a cura do paciente e a preservação do órgão. OBJETIVO: A avaliação dos subsítios na disseminação do carcinoma e a sua influência no tratamento cirúrgico da laringe, no controle local e na sobrevida. MATERIAL E MÉTODO: Cento e sessenta pacientes tratados na Escola Paulista de Medicina - Hospital São Paulo, no período de janeiro de 1998 a dezembro de 2004, foram compilados para análise da disseminação do carcinoma dos subsítios da laringe. Foram incluídos pacientes com seguimento mínimo de 2 anos, após diagnóstico e tratamento. A avaliação estatística foi: Teste X2, Teste de Fisher e a Curva de Kaplan-Meier. Forma de Estudo: Estudo de Coorte Histórica Longitudinal (Trabalho Clínico Retrospectivo). RESULTADOS: A comissura posterior e a infraglote, respectivamente, foram significantes para a laringectomia total: tumores glóticos AC: (p=0,03) AP: (p=0,0001); AC: (p=0,0007) AP: (p<0,0001). A infraglote foi significante nos tumores G+SG na AP: (p=0,04), e na taxa de óbitos AP: (p=0,03). CONCLUSÃO: A laringectomia total é o tratamento de eleição na presença de alto comprometimento da comissura posterior e da infraglote. Esta última pode comprometer a sobrevida, conforme a invasão local, mesmo na presença de margens cirúrgicas livres.

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Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Fatores prognósticos no tratamento do carcinoma epidermóide da laringe: cirurgia conservadora x radical

Vidal

Cervantes

Abrahão

et al. 2007

Rev. Bras. Otorrinolaringol.

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Supracricoid partial laryngectomy as salvage surgery for radiation therapy failure

Deganello¹,

Gallo²,

Cesare³

et al. 2008

Head & Neck

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Background. The main concern in the treatment of laryngeal carcinomas is tumor control with preservation of laryngeal functions. We believe that salvage supracricoid partial laryngectomy (SPL) should be carefully considered in selected cases of radiotherapy failure, because it can offer the possibility of achieving adequate tumor control with preservation of laryngeal functions.Methods. A series of 31 patients who underwent an SPL as salvage procedure after radiotherapy failure was reviewed.Results. Locoregional control rate was 75%, with 60% 5-year overall survival; no patients were lost to follow-up, and a death-from-disease rate of 19.35% was recorded. Restoration of laryngeal functions was achieved in 89.29% of the patients. No statistically significant differences were found in locoregional control regarding anterior commissure involvement, elective neck dissection versus wait-and-see policy, pathologic positive neck disease, and restage I-II versus restage III-IV.Conclusion. The oncologic and functional results indicate the consistency of salvage SPL, proposing this type of operation as a serious alternative to total laryngectomy in carefully selected cases. Keywords: partial laryngectomy; salvage surgery; larynx carcinoma; radiation failure; neck dissectionThe main concern in the treatment of laryngeal carcinomas is tumor control with preservation of whole laryngeal functions.Early laryngeal cancer can be effectively treated either by larynx preserving surgery or with external beam radiation therapy; results in terms of tumor control and preservation of function for both modalities are satisfactory with reported rates of recurrence or persistence of tumor varying from 10% to 35%.

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