Anterior Lens Capsule and Iris Thicknesses in Pseudoexfoliation Syndrome

Batur, Muhammed; Seven, Erbil; Tekın, Serek; Yaşar, Tekin

doi:10.1080/02713683.2017.1338349

Cited by 14 publications

(10 citation statements)

References 21 publications

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“…Especially, iris thickness (IT) (i.e., CT) is a simple morphological parameter to determine the pathology of the iris. A previous study showed that the IT decreased in patients with Fuch’s uveitis,[4] pseudoexfoliation syndrome,[5] neovascular glaucoma,[6,7] and primary congenital glaucoma. [8] In contrast, it increased in patients with sympathetic ophthalmia.…”

Section: Introductionmentioning

confidence: 99%

Determination of iris thickness development in children using swept-source anterior-segment optical coherence tomography

Nakakura¹,

Nagata²,

Shimizu³

et al. 2019

PLoS ONE

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Purpose The uvea comprises the iris, ciliary body, and choroid. However, the development of the anterior part (iris and ciliary body) in children is not yet fully elucidated. We investigated the iris thickness (IT) in children using swept-source anterior-segment optical coherence tomography (ASOCT). Methods In this retrospective, clinic-based study, we enrolled 41 children (mean ± standard deviation: 6.8 ± 3.3 years; range: 3–16; 17 males) with normal or mild refractive error. Horizontal scanning images of swept-source ASOCT were analyzed in temporal and nasal angle areas. The ITs at 1 and 2 mm from the pupil edge were measured using swept-source ASOCT. The association between IT and age, sex, and ocular morphological parameters (i.e., axial length, average corneal curvature, central corneal thickness, inter-scleral spur distance, and anterior chamber depth) was assessed using Pearson’s correlation coefficient (r) and linear regression analysis. Results The average IT (temporal and nasal) at 1 and 2 mm were 0.432 ± 0.060 (0.302−0.569 mm) and 0.337 ± 0.045 (0.229−0.414 mm), respectively. There was a significant correlation between age and average IT ( r = 0.45, P = 0.002 at 1 mm and r = 0.31, P = 0.042 at 2 mm). Multiple linear regression analysis revealed that age (coefficient: 0.01), axial length (−0.02), average corneal curvature (0.01), and anterior chamber depth (0.01) at 1 mm as well as age (0.00), average corneal curvature (0.09), anterior chamber depth (0.06), and male (–0.02) at 2 mm were identified as predictors of IT. Conclusions IT in children increases with age. Additionally, IT was thinner with longer axial length and in males, thicker in eyes with deeper anterior chamber and flatter corneal curvature. Our study may partly explain the development of eyeball structures in children.

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Section: Introductionmentioning

confidence: 99%

Determination of iris thickness development in children using swept-source anterior-segment optical coherence tomography

Nakakura¹,

Nagata²,

Shimizu³

et al. 2019

PLoS ONE

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“…High-resolution OCT allows to evaluate the anterior lens capsule in pseudoexfoliation patients (thicker than in normal patients)[ 38 39 ] and predict postoperative (IOL) tilt, and assist in IOL (toric) power calculations to improve visual outcome after cataract surgery. [ 40 ] Moreover, AS-OCT has been useful to evaluate the wound characteristics of clear corneal incisions of cataract surgery, analyzing incision angle, incision length, corneal thickness, epithelial side closure of the incision or epithelial gaps, endothelial side closure or endothelial gaps, and Descemet's membrane detachment, helping in detecting a high rate of structural abnormalities.…”

Section: Crystalline Lens Assessment and Cataract Surgerymentioning

confidence: 99%

Anterior segment optical coherence tomography for evaluation of cornea and ocular surface

Sridhar

Martín

2018

Indian J Ophthalmol

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“…Згідно з даними різноманітних досліджень, існує різниця між товщиною капсульного мішка у пацієнтів з псевдоексфоліативним синдромом і без нього [7]. За іншими даними різниці у товщині не виявлено [8].…”

Section: вступunclassified

Morphological Estimation of the Biophysical Properties of the Lens Capsule in Patients With Pseudoexfoliative Syndrome

Melnyk¹,

Melnyk²,

Kykot³

2018

Fiziol Zh

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Проведене морфологічне дослідження передньої капсули кришталика у пацієнтів з псевдоексфоліативним синдромом. Отримані результати свідчать, що передня капсула кришталика у них мала більш щільну структуру, її товщина була 21,3±0,7мкм,що в середньому на 55% більше, ніж у групі контролю, а також мала більше шарів епітеальних клітин. Використання передньої капсули кришталика при виконанні антиглаукомної операції-модифікованої тунельної трабекулопунктури покращує гіпотензивний ефект операції за рахунок зазначених особливостей її морфології. Ключові слова: псевдоексфоліативний синдром; глаукома; передня капсула кришталика; модифікована тунельна трабекулопунктура.

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Anterior Lens Capsule and Iris Thicknesses in Pseudoexfoliation Syndrome

Abstract: With high-resolution OCT imaging, it has become possible to evaluate the anterior lens capsule without histologic examination and demonstrate that it is thicker than normal in PEX patients.

Cited by 14 publications

References 21 publications

Determination of iris thickness development in children using swept-source anterior-segment optical coherence tomography

Determination of iris thickness development in children using swept-source anterior-segment optical coherence tomography

Anterior segment optical coherence tomography for evaluation of cornea and ocular surface

Morphological Estimation of the Biophysical Properties of the Lens Capsule in Patients With Pseudoexfoliative Syndrome

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