Anterior Temporal Chordoid Meningioma Causing Compressive Optic Neuropathy

Malloy, Kelly A.; Chigbu, DeGaulle I.

doi:10.1097/opx.0b013e3182114320

Cited by 9 publications

(12 citation statements)

References 30 publications

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“…Nine patients were reviewed from 1743 total meningioma patients in a 1995 to 2013 time period at St. Michael's Hospital in Toronto. To the best of our knowledge, 221 cases of CM have been reported in the English literature worldwide in the form of single case reports and/or case series …”

Section: Discussionmentioning

confidence: 99%

Chordoid meningiomas: Incidence and clinicopathological features of a case series over 18 years

et al. 2014

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Chordoid meningioma (CM) is a rare subtype of meningioma, classified as grade II, which exhibits a high rate of recurrence following subtotal resection. We retrospectively examined nine cases of chordoid meningioma over a case series of 1743 meningiomas (0.52%) operated upon at our institution from 1995 to 2013. All the reported clinicopathological findings were analyzed. Two hundred and twenty-one CM cases have been published to date worldwide and few single-center large case series have been issued. Seventy-five percent of the cases that underwent subtotal resection at our institution had recurrence within 1 year. Total resection of the tumor should be the major objective of surgery to reduce the possibility of tumor recurrence. The percentage of chordoid features within the tumor specimen could assist in predicting the pathogenesis of the lesion. The correlation of the index of proliferation to recurrence rate is still controversial. Much debate exists with regard to the role of adjuvant radiotherapy in CM cases. Immunohistochemical, cytological and ultrastructural studies should be used in combination to assure a correct diagnosis of CM. Owing to the rare occurrence of this meningioma subtype, larger case series are required to assist in providing a reference for diagnosis and to improve the therapeutic management of CM.

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Section: Discussionmentioning

confidence: 99%

Chordoid meningiomas: Incidence and clinicopathological features of a case series over 18 years

et al. 2014

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“…Although sample numbers in the present study were slightly lower than in the series of Couce et al ., the discordance in the MIB‐1 LI raises possible doubts about CM being a malignancy with a truly elevated proliferation potential. Interestingly, it is reported that the MIB‐1 LI was appreciably higher in meningiomas that recurred than those that did not . A recent report suggested that the MIB‐1 LI may be used to predict prognosis in patients with CM, citing the finding that the MIB‐1 LI was increased following tumour recurrence .…”

Section: Discussionmentioning

confidence: 99%

“…Only 120 cases of CM have been reported in the English‐language literature since it was first described in 1988 by Kepes et al . Most of those studies focused only on histopathological, immunohistochemical and cytological aspects, and seldom mentioned its clinical features and recurrence …”

Section: Introductionmentioning

confidence: 99%

Clinical features and treatment of intracranial chordoid meningioma: a report of 30 cases

Mei

Zhao

et al. 2013

Histopathology

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“…Metastasis, infiltration or physical impingement of tumors into or onto peripheral nerves or nerve roots results in neurological symptoms that may lead to initial diagnosis (1-3). Alternatively, tumor-derived factors or sensitized immunological responses may result in paraneoplastic neurological symptoms that range in severity from mild muscle weakness, gait disturbance and minor sensory loss to profound generalized demyelination and severe pain (4-7).…”

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confidence: 99%

Subclinical Peripheral Neuropathy Is a Common Finding in Colorectal Cancer Patients Prior to Chemotherapy

Boyette-Davis

Eng

Wang

et al. 2012

Clinical Cancer Research

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Purpose Of the numerous complications associated with cancer and cancer treatment, peripheral neuropathy is a deleterious and persistent patient complaint commonly attributed to chemotherapy. The present study investigated the occurrence of subclinical peripheral neuropathy in patients with colorectal cancer prior to the initiation of chemotherapy. Experimental Design Fifty-two (52) patients underwent extensive quantitative sensory testing (QST) prior to receiving chemotherapy. Changes in multiple functions of primary afferent fibers were assessed and compared to a group of healthy control subjects. Skin temperature, sensorimotor function, sharpness detection, and thermal detection were measured, as was touch detection, using both conventional (von Frey monofilaments) and novel (Bumps detection test) methodology. Results Patients had subclinical deficits, especially in sensorimotor function, detection of thermal stimuli, and touch detection that were present prior to the initiation of chemotherapy. The measured impairment in touch sensation was especially pronounced when using the Bumps detection test. Conslusions The colorectal cancer patients in this study exhibited deficits in sensory function prior to undergoing chemotherapy treatment, implicating the disease itself as a contributing factor in chemotherapy induced peripheral neuropathy. The widespread nature of the observed deficits further indicated that cancer is affecting multiple primary afferent subtypes. Specific to the finding of impaired touch sensation, results from this study highlight the use of newly employed methodology, the Bumps detection test, as a sensitive and useful tool in the early detection of peripheral neuropathy.

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Anterior Temporal Chordoid Meningioma Causing Compressive Optic Neuropathy

Cited by 9 publications

References 30 publications

Chordoid meningiomas: Incidence and clinicopathological features of a case series over 18 years

Chordoid meningiomas: Incidence and clinicopathological features of a case series over 18 years

Clinical features and treatment of intracranial chordoid meningioma: a report of 30 cases

Subclinical Peripheral Neuropathy Is a Common Finding in Colorectal Cancer Patients Prior to Chemotherapy

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