Anthelmintic Activity of Tanacetum vulgare L. (Leaf and Flower) Extracts against Trichostrongylidae Nematodes in Sheep In Vitro

Kļaviņa, Alīna; Keidāne, Dace; Ganola, Kristīne; Lusis, I.; Šukele, Renāte; Bandere, Dace; Kovaļčuka, Līga

doi:10.3390/ani13132176

Cited by 4 publications

(2 citation statements)

References 47 publications

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“…A study of the human gut microbiome showed positive effects of condensed tannins [ 66 ]. Ruminants can benefit from tannin intake as it reduces bloating and intestinal parasites [ 64 , 68 ]. Tannin metabolism and its relationship with the gut microbiome is complex due to tannins’ structural diversity and high molecular mass.…”

Section: Discussionmentioning

confidence: 99%

The Antioxidant Activity of Wild-Growing Plants Containing Phenolic Compounds in Latvia

Teterovska,

Sile,

Paulausks

et al. 2023

Plants

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Ethnobotanical reports from Latvia show that Tanacetum vulgare, Calluna vulgaris, Quercus robur, Artemisa absinthium, and Artemisia vulgaris contain phenolic compounds that have antioxidant properties, which can be beneficial in the treatment and prophylaxis of many diseases. The aim of this study was to characterize the phenolic compounds and antioxidant properties of these plants. Plant extracts were prepared using ethanol or acetone and then freeze-dried. Their total phenolic content (TPC), total flavonoid content (TFC), and total tannin content (TTC) were determined and characterized by HPLC. Their antioxidant properties were determined using a DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay. C. vulgaris herb and T. vulgare leaf extracts contained the highest amounts of flavonoids, but the bark of Q. robur had mostly tannins and phenolic acids. A. absinthium and A. vulgaris had the lowest amounts of polyphenols. When compared using extraction solvents, all acetone extracts had more TPC, more TFC, and better antioxidant activity. All plants contained chlorogenic acid, which contributes to antioxidant properties. The analysed plant extracts could be used in future studies to develop medicinal products with antioxidant properties.

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Section: Discussionmentioning

confidence: 99%

The Antioxidant Activity of Wild-Growing Plants Containing Phenolic Compounds in Latvia

Teterovska,

Sile,

Paulausks

et al. 2023

Plants

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“…Ellio [24]. The in vitro anthelmintic activity of various tansy inflorescence and leaf extracts was estimated on Trichostrongylidae nematodes in sheep [25]. The cultivation of tansy (and other perennial wild plant species) is an important factor for sustainable bioenergy (biogas) production [26].…”

Section: Introductionmentioning

confidence: 99%

Phytochemistry and Allelopathic Effects of Tanacetum vulgare L. (Tansy) Extracts on Lepidium sativum L. (Garden Pepper Cress) and Lactuca sativa L. (Lettuce)

Judžentienė,

Būdienė,

Stancelytė

et al. 2024

Horticulturae

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Tanacetum vulgare is a perennial plant growing wild along roadsides, pastures, and agricultural fields. Its prevalence is due to several factors: good climatic adaptability, high self-seeding potential, phenotypic plasticity, multiplying via underground rhizomes and its allelochemicals, which influence the seed germination, root development and the overall vegetation of the surrounding plants. The phytochemistry of tansy extracts and their allelopathic activity on the seed germination and growth of garden pepper cress (Lepidium sativum L.) and lettuce (Lactuca sativa L.) were investigated. The major volatile compounds, 1,8-cineole, camphor and borneol were determined in tansy flower extracts. The leaf extracts contained appreciable amounts of 1,8-cineole and borneol. Feruloylquinic, (di)ferulic and dehydrocaffeoyl-5-caffeoylquinic acids, acacetin, ludovicin С and tanacetin were determined both in leaf and inflorescence extracts. Root extracts contained minor quantities of some terpenoids and polyphenols. Extracts of T. vulgare’s aerial parts showed strong allelopathic effects on model plants. The flower and leaf water extracts inhibited lettuce and pepper cress seed germination and growth the most. According to the fractions, the acidic solution had the strongest effect, followed by neutral and alkaline solutions. At the highest relative concentrations of 0.5 and 1.0 tansy leaf acidic fraction, lettuce seed germination and growth decreased by 89.93% (from 35.07 ± 4.79 to 3.53 ± 2.10 mm) and by 98.46% (from 35.07 ± 4.79 to 0.57 ± 0.98 mm) compared to the control, respectively. Tansy root extracts showed weak effects. Our results demonstrated that the allelopathic inhibitory potential of tansy extracts was higher on garden pepper cress than on lettuce. The presence of allelochemicals in T. vulgare may have a significant impact on plant communities and ecosystems.

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Evaluation of the Influence of Tanacetum vulgare Extract on Cognitive Functions and Hippocampal BDNF Expression

Lechkova,

Shishmanova-Doseva,

Benbassat

et al. 2024

Molecules

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Tanacetum vulgare L. has been traditionally applied as a remedy for headaches, rheumatism, digestion, respiratory and neurological problems, and other medical conditions. However, the literature data on its effects on cognitive function are scarce. The aim of the present work was to evaluate the effects of two doses of T. vulgare alcohol extract on cognitive functions, hippocampal brain-derived neurotrophic factor (BDNF) expression, and organ toxicity in rats. Rats were treated with T. vulgare 200 mg/kg (TV 200) and 1000 mg/kg (TV 1000) for 28 days. After one week of pre-treatment, the animals were subjected to a series of tests. We found that in the active avoidance test, only TV 200 improved learning and memory, while in the passive avoidance test, both doses facilitated these processes. In addition, the two doses enhanced spatial memory. In the elevated plus maze test, only the higher dose of TV 1000 resulted in anxiolytic-like behavior. Both doses of the extract significantly increased the hippocampal expression of BDNF. We suggest that increased neurotrophic factor expression could be one of the important mechanisms underlying the cognition-enhancing effects of T. vulgare extract.

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Anthelmintic Activity of Tanacetum vulgare L. (Leaf and Flower) Extracts against Trichostrongylidae Nematodes in Sheep In Vitro

Cited by 4 publications

References 47 publications

The Antioxidant Activity of Wild-Growing Plants Containing Phenolic Compounds in Latvia

The Antioxidant Activity of Wild-Growing Plants Containing Phenolic Compounds in Latvia

Phytochemistry and Allelopathic Effects of Tanacetum vulgare L. (Tansy) Extracts on Lepidium sativum L. (Garden Pepper Cress) and Lactuca sativa L. (Lettuce)

Evaluation of the Influence of Tanacetum vulgare Extract on Cognitive Functions and Hippocampal BDNF Expression

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