Anthelmintic drugs for treating ascariasis

Conterno, Lucieni de Oliveira; Turchi, Marília Dalva; Corrêa, Ione; Almeida, Ricardo Augusto Monteiro de Barros

doi:10.1002/14651858.cd010599.pub2

Cited by 38 publications

(23 citation statements)

References 173 publications

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“…Therefore, when women attend antenatal clinics (ANC), they freely obtain the drugs and take them in as a Directly Observed Treatment (DOT) to improve adherence. However, as reported in other studies regarding drug compliance in pregnancy [ 10 , 11 ], some pregnant women may avoid the drugs due to uncomfortable side effects such as nausea, vomiting, and diarrhoea, associated with chewable mebendazole tablets [ 12 ], especially when given with other routine drugs such as antimalarials (Sulphadoxine Pyrimethamine) for malaria prevention. Therefore, in most ANC situations where monitoring is difficult due to increased workload among ANC care providers, adherence may remain a challenge despite the DOT strategy.…”

Section: Introductionmentioning

confidence: 99%

Factors associated with the use of deworming drugs during pregnancy in Tanzania; an analysis from the 2015–16 Tanzanian HIV and malaria indicators survey

Bankanie

Moshi

2022

BMC Pregnancy Childbirth

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Background The use of deworming drugs is one of the important antenatal strategies in preventing anaemia in pregnancy. Little is known about the factors associated with the use of deworming drugs, which accounts for the aim of this study. Method The study used data from the 2015–16 Tanzania HIV Demographic and Health Survey and Malaria Indicators Survey (2015–16 TDHS-MIS). A total of 6924 women of active reproductive age from 15 to 49 were included in the analysis. Both univariate and multiple logistic regression analyses were used. Results The majority of interviewed women 3864(60.1%) took deworming drugs. In a weighed multiple logistic regression, women residing in urban areas reported greater use of deworming drugs than women residing in rural areas [AOR = 1.73, p = 0.01, 95% CI (1.26–2.38)]. In the four areas of residence, compared to women residing in mainland rural areas, women residing in mainland urban areas and Pemba islands reported greater use of deworming drugs [mainland urban (AOR = 2.56 p < 0.001,95% CI(1.78–3.75), and Pemba Island (AOR = 1.18, p < 0.001, 95% CI(1.17–1.20)]. However, women residing in Zanzibar Island (Unguja) were less likely to use deworming drugs compared to women in mainland rural women (AOR = 0.5, p < 0.001, 95% CI (0.45–0.55). Similarly, compared to women under 20 years of age, women between 20 to 34 years reported significantly greater use of deworming drugs [20 to 34 years (AOR = 1.30, p = 0.03, 95% CI(1.02–1.65). Likewise, greater use of deworming drugs was reported in women with a higher level of education compared to no education [higher education level (AOR = 3.25, p = 0.01,95% CI(1.94–7.92)], rich women compared to poor [rich (AOR = 1.43, p = 0.003, 95% CI (1.13–1.80)] and in women who initiated antenatal care on their first trimester of pregnancy compared to those who initiated later [AOR = 1.37, p < 0.001, 95% CI (1.17–1.61)]. Conclusion Women who were more likely to use the deworming drugs were those residing in urban compared to rural areas, aged between 20 and 34 years, those with a higher level of formal education, wealthier, and women who book the antenatal clinic (ANC) within their first trimester of pregnancy. Considering the outcomes of anaemia in pregnancy, a well-directed effort is needed to improve the use of deworming drugs.

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Section: Introductionmentioning

confidence: 99%

Factors associated with the use of deworming drugs during pregnancy in Tanzania; an analysis from the 2015–16 Tanzanian HIV and malaria indicators survey

Bankanie

Moshi

2022

BMC Pregnancy Childbirth

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“…These drugs inhibit the polymerization of tubulin and microtubule-dependent glucose uptake in these parasites [12]. Albendazole (single oral dose of 400 mg) or mebendazole (single oral dose of 500 mg or 100 mg twice daily for three days) form the cornerstone of management in adult non-pregnant individuals, although it might not prevent reinfection [13]. Adverse effects like nausea, vomiting, abdominal pain and elevation of transaminases might occur, but it does not warrant cessation of therapy.…”

Section: Discussionmentioning

confidence: 99%

Helminthic Infection in the Background of Active Pulmonary Tuberculosis: An Underreported Co-infection

Syal

Arya

HAPANI

et al. 2021

Cureus

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Helminthic infections are widely prevalent in resource-poor countries. Tuberculosis, a disease contributing significantly to morbidity and mortality in endemic areas, often co-exists with helminthic infections. Poor living standards predispose to both of them. Moreover, untreated helminthic infection enhances the deleterious impact of tuberculosis, largely through immunological alteration. We are reporting the case of a 22-year-old male who presented with a month-long history of abdominal pain, nausea, vomiting, fever and cough complicated by hemoptysis, along with an episode of the passage of a worm in the vomitus. A thorough workup revealed active pulmonary tuberculosis co-existing with intestinal ascariasis. Antihelminthic therapy was initiated along with anti-tubercular therapy, leading to significant improvement.

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“…According to a recent Cochrane review, all drugs are equally effective with a single dose being as effective as multiple doses. 131 Complications might require interventions such as ERCP or surgery in case of intestinal obstruction or appendicitis. 129,130 Protozoan parasites: Entamoeba histolytica Amoebiasis is caused by the protozoa Entamoeba histolytica and occurs in humans and primates.…”

Section: Key Pointmentioning

confidence: 99%

Parasites of the liver – epidemiology, diagnosis and clinical management in the European context

Peters¹,

Burkert²,

Grüner

2021

Journal of Hepatology

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Parasites in the liver cause significant global morbidity and mortality, as they can lead to recurrent cholangitis, cirrhosis, liver failure and cancer. Due to climate change and globalisation, their incidence is increasing, especially in Europe. The correct diagnosis of a hepatic parasite is often delayed because clinicians are unfamiliar with respective entities. Therefore, in this review, we aim to provide clinicians with a comprehensive clinical picture of hepatic parasites and to bring these neglected parasitic liver diseases to the wider attention of hepatology stakeholders in Europe and around the world.

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Anthelmintic drugs for treating ascariasis

Abstract: Trusted evidence. Informed decisions. Better health. Cochrane Database of Systematic Reviews Analysis 2.1. Comparison 2 Albendazole 400 mg single dose versus albendazole 400 mg multiple doses, Outcome 1 Parasitological cure (up to 60 days of follow-up

Cited by 38 publications

References 173 publications

Factors associated with the use of deworming drugs during pregnancy in Tanzania; an analysis from the 2015–16 Tanzanian HIV and malaria indicators survey

Factors associated with the use of deworming drugs during pregnancy in Tanzania; an analysis from the 2015–16 Tanzanian HIV and malaria indicators survey

Helminthic Infection in the Background of Active Pulmonary Tuberculosis: An Underreported Co-infection

Parasites of the liver – epidemiology, diagnosis and clinical management in the European context

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