“…Given the harmful impacts on aquatic animals, the environment and human health caused by the overuse of antibiotics and other disease control chemicals (Cabello et al, ; Howard, ; Lazado, Caipang, & Estante, ; Meidong et al, ; Miranda, Tello, & Keen, ; Smith, Harris, Johnson, Silbergeld, & Morris, ), there is an urgent need for the aquaculture industry to find more effective and sustainable reagents to control the diseases. Medicinal plants provide an alternative solution because of their demonstrated medical efficacy and environmental friendliness (Rahuman, Gopalakrishnan, Venkatesan, & Geetha, ; Zhou et al, ).…”