Anthelmintic Resistance Status in Gastrointestinal Nematodes of Seven Different Breeds of Sheep in intensive management

Abstract

The severe use of anthelmintics to control gastrointestinal nematodes has become an essential issue in many countries, especially related to resistance issues. A study was carried out to determine the anthelmintic resistance status of intestinal nematodes of sheep, which were kept intensively in Bogor District, Indonesia. A total of 220 sheep of 7 breeds that routinely received Benzimidazole anthelmintics group to control gastrointestinal nematode were designated for this study. The animals were divided into 7 groups based on the breed and treated with Albendazole at the required dose. The Fecal Egg Count Reduction Test (FECRT) method was used to evaluate the anthelmintic’s effectiveness. The mean fecal egg count reduction was recorded at seven and fourteen days of treatment. The result indicated that 7 breeds of sheep were resistant to the anthelmintic used. Garut Local and Barbados Cross breeds showed relatively high resistance to Albendazole, with the mean fecal egg count at fourteen days of treatment being 60.24% and 67.97%, respectively. Haemonchus spp. larvae were the nematode larvae of strongyles species that grew the most in each breed of sheep from the fecal samples on day 0 (before treatment), day 7, and day 14 after treatment.

Assessing the In Vitro Individual and Combined Effect of Arthrobotrys Oligospora and <em>A. musiformis</em> (Orbiliales) Liquid Culture Filtrates against Infective Larvae of the Sheep Blood-Feeding Nematode <em>Haemonchus contortus</em> (Trichostrongylidae)

“…This and other genera/species of parasitic nematodes live in the gastrointestinal tract of small ruminants, where they cause severe deterioration of flock health and productivity. Gastrointestinal nematodiasis is controlled by the frequent and continuous administration of chemical anthelmintic drugs to the animals; however, the development of anthelmintic resistance in the parasites occasions an increasing inefficacy of these drugs that has raised the alarm regarding the use of these drugs by farmers around the world [3,4]. During recent decades, strategies other than the use of chemical anthelmintic drugs have been explored, including the use of natural antagonists of nematodes, such as a group of microfungi called nematode-trapping fungi [5,6].…”

Assessing the In Vitro Individual and Combined Effect of Arthrobotrys oligospora and A. musiformis (Orbiliales) Liquid Culture Filtrates against Infective Larvae of the Sheep Blood-Feeding Nematode Haemonchus contortus (Trichostrongylidae)

“…This and other genera/species of parasitic nematodes live in the gastrointestinal tract of small ruminants, where they cause severe deterioration of flock health and productivity. Gastrointestinal nematodiasis is controlled by the frequent and continuous administration of chemical anthelmintic drugs to the animals; however, the development of anthelmintic resistance in parasites has led to increasing inefficacy of these drugs, raising alarm among farmers worldwide [3,4]. During recent decades, strategies other than the use of chemical anthelmintic drugs have been explored, including the use of Pathogens 2024, 13, 498 2 of 18 natural antagonists of nematodes, such as a group of micro-fungi called nematode-trapping fungi [5,6].…”