Anthelmintic resistance to cattle gastrointestinal nematodes in selected dairy farms of Mymensingh and Sirajganj districts of Bangladesh

Abstract

Correction: Table 1 and Table 2 have were omitted from the PDF in error. They were added to page 89 on 17th May 2018.Anthelmintic resistance (AR) to commonly used dewormers is one of the major world-wide constrain in livestock production. The present study was investigated the status of AR in BAU dairy farm, Mymensingh and Talukder dairy farm, Sirajganj. Faecal egg count reduction test (FECRT) was applied to assess AR in cattle of two dairy farms during January to June 2017. The anthelmintics tested were Albendazole (ABZ), a benzimidazole anthelmintic (Almex®, Square Ltd.) and Ivermectin (IVM) (Vermic®, Techno drugs Ltd.), administered at the doses recommended by the manufacturers. In each farm, cattle were divided into treatment and control (not treated) group based on faecal egg counts (FEC), that is at least 200 eggs/g. At 14 days after treatment, faecal samples were collected for post-treatment FEC, which is compared between treatment and control group. Resistance was defined if there was <95% reduction, with lower 95% confidence limit (CL) <90% in the FEC. AR was present in both the dairy farms involved in this study. The FECRT using ABZ revealed 79.7% (95% CL 87.9, 65.8) reduction and 95.8% (95% CL 98.7, 87.1) reduction of FEC in BAU and Talukder dairy farms, respectively. Also, FECRT using IVM revealed 77.9% (95% CL 97.7, 85.5) and 94.2% (95% CL 97.7, 85.5) reduction of FEC in BAU and Talukder dairy farms, respectively. Our study suggest that AR is present in both selected dairy farms and further extensive studies are required to determine the extent of AR in different cattle farms of Bangladesh.Res. Agric., Livest. Fish.5(1): 87-92, April 2018

Efficacy of Locally Available Anthelmintics against Helminths of Dairy Cows in Gazipur, Bangladesh

“…Anthelmintic resistance is a global problem in the livestock industry with severe consequences in emerging countries because of indiscriminate use and huge consumption of anthelmintics in livestock farming, lack of education, lack of awareness, compromised immunity, inability to purchase more effective but costly anthelmintics, underdosing, undernutrition, and a habit of self-administration of anthelmintics to the livestock by farmers (Rahman et al, 2018). Previously resistance of Fasciola spp.…”

“…Many trials have estimated the effects of gastrointestinal helminths by measuring the association between infection levels and production parameters or by assessing the effect of anthelmintic treatment on production traits (Vercruysse and Claerebout, 2001;Smith, 1997). The distribution of parasites in adult dairy cows is overdispersed (Agneessens et al, 2000;Borgsteede et al, 2000; and the prevalence of gastrointestinal helminths in dairy cows were determined previously in different areas of Bangladesh (Alim et al, 2012;Islam et al, 2015;Rahman et al, 2018). It is evident from either artificial infection or anthelmintic control studies that helminths have several adverse impacts on dairy cows, including effects on milk production, suckler calf weaning weight and fertility (Hawkins, 1993).…”

“…Due to the negative effects of parasites on dairy cows, it is essential to control parasitic diseases in dairy animals. In the absence of other alternatives, parasite control continues to rely on anthelmintics because of their high performance and their use is likely to continue in the foreseeable future as the first and foremost line of defence against parasites (Martin, 1985;Rahman et al, 2018). Because of the haphazard and extensive use of anthelmintics, the helminth parasites become resistant to commonly used anthelmintics and ultimately treatment failure occurs (Besier, 2007).…”

“…There is a scarcity of studies to determine the resistance of locally available anthelmintics against helminths in Bangladesh (Rahman et al, 2018;Hoque et al, 2003). By considering the above facts, the present work has been undertaken to obtain detailed information on the parasitic infestation in dairy cows and evaluate the efficacy of some locally available anthelmintics and the degree of resistance (if any) against helminth parasites in some selected dairy farms of Gazipur district, Bangladesh.…”