2023
DOI: 10.1002/fsn3.3923
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Anthocyanins from Lycium ruthenicum Murray attenuates high‐fat diet‐induced hypercholesterolemia in ApoE−/− mice are related to the modulation of gut microbiota and the ratio of conjugated to unconjugated bile acids in fecal bile acid profile

Meng Zhang,
Hui Li,
Tingting Tan
et al.

Abstract: Previous findings showed that anthocyanins from Lycium ruthenicum Murray (ACN) reduced HFD‐induced hypercholesterolemia by regulating gut microbiota, but the mechanism has not been fully understood. The objective of this research was to know whether the cholesterol‐lowering impact of ACN in HFD‐induced ApoE−/− mice is related to the gut microbiota‐bile acid (BA) metabolism. Twenty‐four male ApoE−/− mice were divided into three groups: the Control group, the HFD group, and the HFD + ACN group. Here, we showed t… Show more

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