Anthropological and socioeconomic factors contributing to global antimicrobial resistance: a univariate and multivariable analysis

Abstract

None.

An urgent need for antimicrobial stewardship in Indigenous rural and remote primary health care

“…A critical knowledge gap is the relative contribution of the social determinants of health to AMR in remote communities. Overseas studies have linked community poverty to AMR and underscored the importance of poor sanitation and access to clean water as drivers of AMR spread . AMR in remote Australian communities will likely continue increasing unless infections are prevented, thus reducing the need for antimicrobial use.…”

“…Overseas studies have linked community poverty 20 to AMR and underscored the importance of poor sanitation and access to clean water as drivers of AMR spread. 21 AMR in remote Australian communities will likely continue increasing unless infections are prevented, thus reducing the need for antimicrobial use. Improving housing (quantity and quality), health care literacy and access, and availability of functioning health hardware will limit transmission of AMR pathogens (the concept of reducing contagion 21 ).…”

Complexities in understanding antimicrobial resistance across domesticated animal, human, and environmental systems

“…Antimicrobial resistance (AMR) is a global problem that impacts both human and animal health. Although AMR primarily derives from antibiotic and antimicrobial use, strong evidence suggests that wider spread of AMR is fueled by inadequate local sanitation, pollution, and other nonuse factors, with the natural environmental being an important conduit . Explaining AMR and then developing informed approaches to mitigate it are difficult because many technical, scientific, and behavioral factors come into play.…”

“…Although AMR primarily derives from antibiotic and antimicrobial use, strong evidence suggests that wider spread of AMR is fueled by inadequate local sanitation, pollution, and other nonuse factors, with the natural environmental being an important conduit. [1][2][3] Explaining AMR and then developing informed approaches to mitigate it are difficult because many technical, scientific, and behavioral factors come into play. Factors range from understanding the evolution of resistance at the molecular level within a given organism, to transmission mechanisms and pathways across organisms, to wider dissemination between human and animal hosts and across the wider environment, including soil and water.…”

Vaccine innovations for emerging infectious diseases—a symposium report

“…Srikantiah was encouraged that the report included vaccine development as one of its interventions, but noted that vaccines do not receive as much attention for their potential to address AMR as other strategies, such as antibiotic stewardship, promoting new diagnostics, or developing new antimicrobials for drug‐resistant organisms. While reducing antibiotic use is undoubtedly an important part of limiting AMR, additional strategies are needed …”