Anthropometric Correlation with Pathophysiology of Obstructive Sleep Apnea (OSA): A Review

Thukral, Himanshu; Gupta, Gaurav; Sinha, Sanjeev; Garg, Ravinder

doi:10.1007/s41782-020-00089-2

Cited by 5 publications

(4 citation statements)

References 72 publications

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“…Surprisingly in our study, there was no positive statistical correlation between nasal septum deviation and hypertrophy of the turbinates; the reason behind this situation is probably the high presence of these pathologies that are neglected for long periods of time in the general population of Romania [58][59][60].…”

Section: Discussioncontrasting

confidence: 87%

Correlations between Morphology, the Functional Properties of Upper Airways, and the Severity of Sleep Apnea

Neagoş

Dumitru

Neagos

et al. 2022

JCM

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Obstructive sleep apnea (OSA) is considered the silent killer pathology of the new millennium. This is due to increased risk factors such as obesity. Healthcare systems face an increasing burden from severe cases of OSA. We performed a study on a group of 152 Romanian patients with OSA recording data obtained through polysomnography and cephalometric variables, recorded in lateral plain X-rays. The results confirmed some of the data available from previous studies worldwide, but some of the variables presented a positive statistical correlation specific to our study group. For example, the apnea-hypopnea index (AHI) correlated with the uvula length but surprisingly did not correlate with body mass index (BMI) because obesity tends to become endemic in Romania. To our knowledge, this is one of the first studies focusing on cephalometric data in Romanian OSA patients. The results obtained through this study will be further analyzed in research on larger groups of Romanian OSA patients.

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Section: Discussioncontrasting

confidence: 87%

Correlations between Morphology, the Functional Properties of Upper Airways, and the Severity of Sleep Apnea

Neagoş

Dumitru

Neagos

et al. 2022

JCM

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“…Previous studies have suggested that BMI and WHR are more significant risk factors for OSA exacerbation in men. According to Himanshu et al, approximately 30% of individuals with a BMI greater than 30 kg/m2 and 50% of individuals with a BMI greater than 40 kg/m 2 had OSAS [ 29 ].…”

Section: Discussionmentioning

confidence: 99%

Understanding the Association Between Obesity and Obstructive Sleep Apnea Syndrome: A Case-Control Study

Patial,

Mishra,

Pal

et al. 2023

Cureus

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Introduction Obstructive sleep apnea (OSA) represents a sleep-related impairment linked to upper airway function. The question of whether OSA drives obesity or if shared underlying factors contribute to both conditions remains unresolved. Hence, this present study aims to understand the interplay between obstructive sleep apnea syndrome (OSAS) and obesity through in-depth analysis of anthropometric data within control subjects and OSA patients. Methodology A case-control study was conducted, which included 40 cases and 40 matched healthy controls. Study participants with reported symptoms of snoring, daytime drowsiness, or both were included in the study. All the study participants underwent comprehensive anthropometric assessments such as height, weight, body mass index (BMI), neck circumference, waist circumference, hip circumference, waist-to-hip ratio, skin-fold thickness, and thickness measurements of biceps, triceps, suprailiac, and subscapular muscles. Results Within the OSA group, significant disparities emerged in mean age, waist circumference, waist-to-hip ratio, and diverse fat accumulations encompassing visceral, subcutaneous, trunk, and subcutaneous leg fat. Notably, skin-fold thickness at specific sites - biceps, triceps, subscapula, and suprailiac - demonstrated considerable augmentation relative to the control group. Furthermore, mean values associated with height, weight, BMI, neck circumference, fat percentage, subcutaneous arm fat, entire arm composition, and trunk skeletal muscle either equaled or exceeded those in the control group. However, statistical significance was not attained in these comparisons. Conclusion This investigation underscored a pronounced correlation between numerous endpoints characterizing OSA patients and markers of obesity. Consequently, addressing altered levels of obesity-linked anthropometric variables through pharmacological interventions might hold promise as a pivotal strategy for improving symptoms associated with OSA.

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“…This follows hypoxia and hypercapnia, which leads to an increase in ventilator effort that causes awakening. Pharyngeal muscle activity and upper airway entry open rapidly upon arousal, and the patient hyperventilates to compensate for hypercapnia and hypoxia (Figure 1 ) [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Atrial Fibrillation in Obstructive Sleep Apnea Patients: Mechanisms, Risk Factors, and Management Strategies

Sankaranarayanan¹,

Bansal²,

Yanamaladoddi³

et al. 2023

Cureus

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Obstructive sleep apnea (OSA) is identified by apnea or hypopnea of the upper respiratory tract, which is associated with decreased oxygen saturation or awakening from sleep. A severe and prevalent association with OSA is atrial fibrillation (AF). This review article outlined numerous studies to understand the pathogenic pathways linked with developing OSA-associated AF and the therapeutic and preventive options available to reduce AF. The article looked for multiple risk factors common to OSA and AF. In addition, it has reviewed several therapeutic modalities such as continuous positive air pressure (CPAP), weight loss, upper airway stimulation (UAS), and other novel treatment options to find their efficiency in decreasing the outcome of AF in OSA patients. Since OSA often goes undiagnosed, this article emphasizes the importance of early screening in patients with AF and other comorbid conditions such as obesity, advanced age, diabetes, hypertension, and many more. The article focuses on the importance of preventive approaches that can be easily implemented, such as behavioral modifications.

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Anthropometric Correlation with Pathophysiology of Obstructive Sleep Apnea (OSA): A Review

Cited by 5 publications

References 72 publications

Correlations between Morphology, the Functional Properties of Upper Airways, and the Severity of Sleep Apnea

Correlations between Morphology, the Functional Properties of Upper Airways, and the Severity of Sleep Apnea

Understanding the Association Between Obesity and Obstructive Sleep Apnea Syndrome: A Case-Control Study

Atrial Fibrillation in Obstructive Sleep Apnea Patients: Mechanisms, Risk Factors, and Management Strategies

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